The adenosine A2a receptor belongs to the seven transmembrane helix G‐protein‐coupled
receptor family, is abundant in striatum, vasculature and platelets and is involved in several …

The A 2a adenosine receptor, a member of the G protein-coupled receptor family, is
important in the regulation of dopaminergic pathways of the brain and in platelet and …

We report the cloning of the cDNA encoding the homolog of the A3 adenosine receptor
(A3AR) from a human heart library. The receptor shares a surprisingly low degree of …

The actions of the neurotransmitter adenosine are mediated by a family of high‐affinity, G
protein‐coupled receptors. We have characterized the gene for the human A2a subtype of …

The adenosine A2A receptor (A2AR) plays a key role in transmembrane signaling mediated
by the endogenous agonist adenosine. Here, we describe the crystal structure of human …

The G-protein coupled receptors (GPCRs) are a class of membrane proteins that trigger
cellular responses to external stimuli, and are believed to be targets for nearly half of all …

CHO cells stably transfected with adenosine receptors are widely utilized models for binding
and functional studies. The effector coupling of human A3 adenosine receptors expressed in …

The A 2a adenosine receptor is a member of the G-protein coupled receptor family, and its
activation stimulates cyclic AMP production. To determine the residues which are involved in …

A novel receptor cDNA was isolated from a human hippocampal cDNA library. The encoded
polypeptide contains structural features consistent with its classification as a G protein …

To provide insights into interactions between ligands and A2A adenosine receptors, site-
directed mutagenesis was used to test the roles of a glutamic acid residue in the first …