MINI-review of Epstein-Barr virus involvement in multiple sclerosis etiology and pathogenesis

F Aloisi, AH Cross - Journal of Neuroimmunology, 2022 - Elsevier
Epstein-Barr virus (EBV) is the infectious agent that shows the strongest association with
multiple sclerosis (MS). EBV is a ubiquitous double stranded DNA herpes virus that …

Epstein–Barr virus and multiple sclerosis: moving from questions of association to questions of mechanism

OG Thomas, A Rickinson… - Clinical & Translational …, 2023 - Wiley Online Library
Abstract The link between Epstein–Barr virus (EBV) and multiple sclerosis (MS) has puzzled
researchers since it was first discovered over 40 years ago. Until that point, EBV was …

The role of Epstein-Barr virus in the etiology of multiple sclerosis: a current review

K Ruprecht - Expert review of clinical immunology, 2020 - Taylor & Francis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the
central nervous system. While its exact etiology is unknown, it is generally believed that MS …

Trigger, pathogen, or bystander: the complex nexus linking Epstein–Barr virus and multiple sclerosis

GP Owens, JL Bennett - Multiple Sclerosis Journal, 2012 - journals.sagepub.com
A causal role for virus infection in the pathophysiology of multiple sclerosis (MS) has been
suggested and widely debated since the landmark epidemiologic studies of Kurtzke …

Epstein–Barr virus and multiple sclerosis

M Salvetti, G Giovannoni, F Aloisi - Current opinion in neurology, 2009 - journals.lww.com
Epstein–Barr virus and multiple sclerosis : Current Opinion in Neurology Epstein–Barr virus
and multiple sclerosis : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe …

[HTML][HTML] Epstein-Barr virus is present in the brain of most cases of multiple sclerosis and may engage more than just B cells

A Hassani, JR Corboy, S Al-Salam, G Khan - PloS one, 2018 - journals.plos.org
Multiple sclerosis (MS) is a chronic neuroinflammatory condition of the central nervous
system (CNS). It is a major cause of neurological disability in young adults, particularly …

Epstein–Barr virus infection and multiple sclerosis: a review

A Ascherio, KL Munger - Journal of Neuroimmune Pharmacology, 2010 - Springer
Epstein–Barr virus (EBV) infection results in a life-long persistence of the virus in the host's B-
lymphocytes and has been associated with numerous cancers including Burkitt's lymphoma …

Epstein–Barr virus and multiple sclerosis

D Pohl - Journal of the Neurological Sciences, 2009 - Elsevier
Epstein–Barr virus (EBV) is a human DNA herpesvirus infecting more than 90% of the
world's population. EBV is the etiological agent of infectious mononucleosis (Pfeiffer's …

Epstein–Barr virus and multiple sclerosis. From evidence to therapeutic strategies

S Fernández-Menéndez, M Fernández-Morán… - Journal of the …, 2016 - Elsevier
Multiple sclerosis is caused by a complex interaction between genetic predisposition and
environmental factors. Epstein–Barr virus (EBV) is an environmental risk factor that is …

[HTML][HTML] Altered immune response to the epstein–barr virus as a prerequisite for multiple sclerosis

F Läderach, C Münz - Cells, 2022 - mdpi.com
Strong epidemiologic evidence links Epstein–Barr virus (EBV) infection and its altered
immune control to multiple sclerosis (MS) development. Clinical MS onset occurs years after …