Systemic inflammation and comorbidity in COPD: a result of 'overspill'of inflammatory mediators from the lungs? Review of the evidence

NJ Sinden, RA Stockley - Thorax, 2010 - thorax.bmj.com
Chronic obstructive pulmonary disease (COPD) is characterised by an inflammatory
response by the lungs to inhaled substances such as cigarette smoking and air pollutants. In …

Chronic obstructive pulmonary disease• 5: Systemic effects of COPD

E Wouters - Thorax, 2002 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) is characterised by the progressive
development of airflow limitation that is not fully reversible. The clinical syndrome of COPD …

Systemic inflammation in chronic obstructive pulmonary disease

EJD Oudijk, JWJ Lammers… - European Respiratory …, 2003 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is characterised by a chronic inflammation
in the pulmonary tissue. The disease is associated with a switch from a selflimiting …

Systemic effects of chronic obstructive pulmonary disease

AGN Agusti, A Noguera, J Sauleda… - European …, 2003 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is characterised by an inappropriate/
excessive inflammatory response of the lungs to respiratory pollutants, mainly tobacco …

Inflammation of the airways and lung parenchyma in COPD: role of T cells

MG Cosio, J Majo, MG Cosio - Chest, 2002 - Elsevier
A smoking-induced inflammatory reaction in the airways and lung parenchyma, comprised
mainly of neutrophils and alveolar macrophages, has long been accepted to be the major …

Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis

WQ Gan, SFP Man, A Senthilselvan, DD Sin - Thorax, 2004 - thorax.bmj.com
Background: Individuals with chronic obstructive pulmonary disease (COPD) are at
increased risk of cardiovascular diseases, osteoporosis, and muscle wasting. Systemic …

Pathogenesis of COPD. Part III. Inflammation in COPD [State of the Art Series. Chronic obstructive pulmonary disease in high-and low-income countries. Edited by G …

M Roth - The International Journal of Tuberculosis and Lung …, 2008 - ingentaconnect.com
Chronic obstructive pulmonary disease (COPD) is mostly caused by cigarette smoking and
affects up to 25% of smokers. Air pollution and occupational exposure to dust and fumes can …

[HTML][HTML] Chronic Obstructive Pulmonary Disease, inflammation and co-morbidity–a common inflammatory phenotype?

MJ Sevenoaks, RA Stockley - Respiratory research, 2006 - Springer
Abstract Chronic Obstructive Pulmonary Disease (COPD) is and will remain a major cause
of morbidity and mortality worldwide. The severity of airflow obstruction is known to relate to …

[HTML][HTML] Systemic inflammation in chronic obstructive pulmonary disease: a population-based study

F Garcia-Rio, M Miravitlles, JB Soriano, L Muñoz… - Respiratory …, 2010 - Springer
Background Elevated circulating levels of several inflammatory biomarkers have been
described in selected patient populations with COPD, although less is known about their …

Chronic obstructive pulmonary disease as a systemic disease: an epidemiological perspective

H Andreassen, J Vestbo - European Respiratory Journal, 2003 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) has been increasingly recognised as a
systemic disease. The hormonal, metabolic and musculoskeletal implications of the …