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[HTML][HTML] A novel phytochemical, DIM, inhibits proliferation, migration, invasion and TNF-α induced inflammatory cytokine production of synovial fibroblasts from …

H Du, X Zhang, Y Zeng, X Huang, H Chen… - Frontiers in …, 2019 - frontiersin.org
In rheumatoid arthritis (RA) pathogenesis, activated RA fibroblast-like synoviocytes (RA-
FLSs) exhibit similar proliferative features as tumor cells and subsequent erosion to cartilage …
被引用次数：108 相关文章 所有 6 个版本

Diosmetin exhibits anti‐proliferative and anti‐inflammatory effects on TNF‐α‐stimulated human rheumatoid arthritis fibroblast‐like synoviocytes through regulating the …

Y Chen, Y Wang, M Liu, B Zhou… - Phytotherapy …, 2020 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by inflammation
and proliferation of synovial tissues. Diosmetin is a bioflavonoid possessing an anti …
被引用次数：57 相关文章 所有 6 个版本

Resveratrol inhibits TNF-α-induced IL-1β, MMP-3 production in human rheumatoid arthritis fibroblast-like synoviocytes via modulation of PI3kinase/Akt pathway

J Tian, J Chen, J Gao, L Li, X Xie - Rheumatology international, 2013 - Springer
Abstract Resveratrol (trans-3, 4′-trihydroxystilbene), a natural phytoalexin, possesses anti-
inflammatory, anti-proliferative, and immunomodulatory properties and has the potential for …
被引用次数：161 相关文章 所有 11 个版本

Matrine inhibits synovial angiogenesis in collagen-induced arthritis rats by regulating HIF-VEGF-Ang and inhibiting the PI3K/Akt signaling pathway

L Ao, H Gao, L Jia, S Liu, J Guo, B Liu, Q Dong - Molecular Immunology, 2022 - Elsevier
Matrine (Mat) is an alkaloid of tetracycline quinazine, and previous studies have
demonstrated its specific effect on relieving rheumatoid arthritis (RA). However, the effect of …
被引用次数：23 相关文章 所有 4 个版本
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Punicalagin inhibited inflammation and migration of fibroblast-like synoviocytes through NF-κB pathway in the experimental study of rheumatoid arthritis

M Huang, K Wu, S Zeng, W Liu, T Cui… - Journal of …, 2021 - Taylor & Francis
Background The aggressive phenotype of fibroblast-like synoviocytes (FLSs) is essential in
the synovitis and bone destruction in rheumatoid arthritis (RA). Punicalagin is a natural …
被引用次数：41 相关文章 所有 10 个版本
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[HTML][HTML] Tanshinone IIA suppresses proliferation and inflammatory cytokine production of synovial fibroblasts from rheumatoid arthritis patients induced by TNF-α and …

H Du, Y Wang, Y Zeng, X Huang, D Liu, L Ye… - Frontiers in …, 2020 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic and progressive autoimmune disease in which
activated RA fibroblast-1ike synoviocytes (RA-FLSs) are one of the main factors responsible …
被引用次数：44 相关文章 所有 6 个版本

Kaempferol inhibits the migration and invasion of rheumatoid arthritis fibroblast-like synoviocytes by blocking activation of the MAPK pathway

D Pan, N Li, Y Liu, Q Xu, Q Liu, Y You, Z Wei… - International …, 2018 - Elsevier
In rheumatoid arthritis (RA), fibroblast-like synoviocytes (FLSs) play an essential role in
cartilage destruction. Aggressive migration and invasion by FLSs significantly affect RA …
被引用次数：101 相关文章 所有 3 个版本

Genkwanin ameliorates adjuvant-induced arthritis in rats through inhibiting JAK/STAT and NF-κB signaling pathways

Y Bao, YW Sun, J Ji, L Gan, CF Zhang, CZ Wang… - Phytomedicine, 2019 - Elsevier
Background Genkwanin is a flavone isolated from the traditional Chinese herb Daphne
genkwa. Our previous work proved that four flavonoids (including genkwanin) isolated from …
被引用次数：79 相关文章 所有 6 个版本
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[HTML][HTML] Anti-rheumatic properties of gentiopicroside are associated with suppression of ROS-NF-κB-NLRP3 axis in fibroblast-like synoviocytes and NF-κB pathway in …

M Wang, H Li, Y Wang, Y Hao, Y Huang… - Frontiers in …, 2020 - frontiersin.org
Rheumatoid arthritis (RA) is among the most prevalent forms of autoimmunity.
Gentiopicroside (Gent) is an iridoid glucoside derived from the Gentiana Macrophylla Pall …
被引用次数：41 相关文章 所有 7 个版本
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[HTML][HTML] Advances of the small molecule drugs regulating fibroblast-like synovial proliferation for rheumatoid arthritis

Y Tong, X Li, Q Deng, J Shi, Y Feng… - Frontiers in Pharmacology, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is a type of chronic autoimmune and inflammatory disease. In the
pathological process of RA, the alteration of fibroblast-like synoviocyte (FLS) and its related …
被引用次数：11 相关文章 所有 5 个版本