Loss of gut microbial diversity,,,,–in industrial populations is associated with chronic
diseases, underscoring the importance of studying our ancestral gut microbiome. However …

The genome sequences of many species of the human gut microbiome remain unknown,
largely owing to challenges in cultivating microorganisms under laboratory conditions. Here …

The composition of the human gut microbiota is linked to health and disease, but knowledge
of individual microbial species is needed to decipher their biological roles. Despite …

The human gut microbiome plays an important role in health, but its archaeal diversity
remains largely unexplored. In the present study, we report the analysis of 1,167 …

Reference genomes are essential for metagenomic analyses and functional characterization
of the human gut microbiota. We present the Culturable Genome Reference (CGR), a …

In an effort to better understand the ancestral state of the human distal gut microbiome, we
examine feces retrieved from archaeological contexts (coprolites). To accomplish this, we …

Background The Human Microbiome Project (HMP) is one of the US National Institutes of
Health Roadmap for Medical Research. Primary interests of the HMP include the …

Background Humans have coevolved with microbial communities to establish a mutually
advantageous relationship that is still poorly characterized and can provide a better …

Metagenome-based resources have revealed the diversity and function of the human gut
microbiome, but further understanding is limited by insufficient genome quality and a lack of …

Coevolution of mammals and their gut microbiota has profoundly affected their radiation into
myriad habitats. We used shotgun sequencing of microbial community DNA and targeted …