Extracellular Vesicles from Cryptococcus neoformans Modulate Macrophage Functions
DL Oliveira, CG Freire-de-Lima… - Infection and …, 2010 - Am Soc Microbiol
Cryptococcus neoformans and distantly related fungal species release extracellular vesicles
that traverse the cell wall and contain a varied assortment of components, some of which …
that traverse the cell wall and contain a varied assortment of components, some of which …
Extracellular Vesicles Produced by Cryptococcus neoformans Contain Protein Components Associated with Virulence
ML Rodrigues, ES Nakayasu, DL Oliveira… - Eukaryotic …, 2008 - Am Soc Microbiol
Cryptococcus neoformans produces vesicles containing its major virulence factor, the
capsular polysaccharide glucuronoxylomannan (GXM). These vesicles cross the cell wall to …
capsular polysaccharide glucuronoxylomannan (GXM). These vesicles cross the cell wall to …
Interaction of Cryptococcus neoformans extracellular vesicles with the cell wall
JM Wolf, J Espadas-Moreno, JL Luque-Garcia… - Eukaryotic …, 2014 - Am Soc Microbiol
Cryptococcus neoformans produces extracellular vesicles containing a variety of cargo,
including virulence factors. To become extracellular, these vesicles not only must be …
including virulence factors. To become extracellular, these vesicles not only must be …
Phospholipids Trigger Cryptococcus neoformans Capsular Enlargement during Interactions with Amoebae and Macrophages
CJ Chrisman, P Albuquerque, AJ Guimaraes… - PLoS …, 2011 - journals.plos.org
A remarkable aspect of the interaction of Cryptococcus neoformans with mammalian hosts is
a consistent increase in capsule volume. Given that many aspects of the interaction of C …
a consistent increase in capsule volume. Given that many aspects of the interaction of C …
Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide …
SC Tucker, A Casadevall - Proceedings of the National …, 2002 - National Acad Sciences
Cryptococcus neoformans (CN), an encapsulated, ubiquitous environmental yeast, is
pathogenic for humans, primarily those with compromised immune function. CN is believed …
pathogenic for humans, primarily those with compromised immune function. CN is believed …
Growth inhibition of Cryptococcus neoformans by cultured human monocytes: role of the capsule, opsonins, the culture surface, and cytokines
SM Levitz, TP Farrell - Infection and immunity, 1990 - Am Soc Microbiol
Despite a presumed critical role of macrophages in the host response to cryptococcal
infections, previous studies have failed to show growth inhibition of encapsulated …
infections, previous studies have failed to show growth inhibition of encapsulated …
Lipophilic Dye Staining of Cryptococcus neoformans Extracellular Vesicles and Capsule
Cryptococcus neoformans is an encapsulated yeast that causes systemic mycosis in
immunosuppressed individuals. Recent studies have determined that this fungus produces …
immunosuppressed individuals. Recent studies have determined that this fungus produces …
Cell-to-cell spread and massive vacuole formation after Cryptococcus neoformans infection of murine macrophages
M Alvarez, A Casadevall - BMC immunology, 2007 - Springer
Background The interaction between macrophages and Cryptococcus neoformans (Cn) is
critical for containing dissemination of this pathogenic yeast. However, Cn can either lyse …
critical for containing dissemination of this pathogenic yeast. However, Cn can either lyse …
A major role for capsule-independent phagocytosis-inhibitory mechanisms in mammalian infection by Cryptococcus neoformans
CD Chun, JCS Brown, HD Madhani - Cell host & microbe, 2011 - cell.com
The antiphagocytic polysaccharide capsule of the human fungal pathogen Cryptococcus
neoformans is a major virulence attribute. However, previous studies of the pleiotropic …
neoformans is a major virulence attribute. However, previous studies of the pleiotropic …
Role of the capsule in phagocytosis of Cryptococcus neoformans
TR Kozel, GST Pfrommer, AS Guerlain… - Reviews of infectious …, 1988 - JSTOR
The capsule is closely associated with the virulence of Cryptococcus neoformans. The
capsule inhibits phagocytosis by macrophages, monocytes, and neutrophils. Studies in our …
capsule inhibits phagocytosis by macrophages, monocytes, and neutrophils. Studies in our …
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