Impact of different manufacturers and gauge sizes on the performance of backflush needle

H Imai, A Tetsumoto, H Yamada, M Nakamura - Scientific Reports, 2020 - nature.com
The present study aimed to identify the factors regulating aspiration rate (AR) of backflush
needles and to compare those factors across various backflush needles from different …

Suck-back impact on fluid behavior at filling needle tip

MCN Silva, JR Authelin, D Quéré, C Pellet - Journal of Pharmaceutical …, 2020 - Elsevier
Needle clogging induces several issues during the filling step of injectable drugs, which
makes essential to avoiding it to ensure a favorable outcome for the process. The suck-back …

The influence of tip shape on bending force during needle insertion

NJ Van De Berg, TL De Jong, DJ Van Gerwen… - Scientific reports, 2017 - nature.com
Steering of needles involves the planning and timely modifying of instrument-tissue force
interactions to allow for controlled deflections during the insertion in tissue. In this work, the …

Bacterial contamination upon the opening of injection needles

S Abe, I Haraga, F Kiyomi, H Kumano, A Gohara… - JA Clinical Reports, 2018 - Springer
Introduction Two opening methods are used for injection needle products: the “peel-apart
method” where the adhesive surface of the packaging mount is peeled off, and the “push-off …

Optical sensor for the needle lift detection in the common rail injector

C Coratella, L Parry, A Sahu, H Xu - 2019 - sae.org
The detection of needle displacement within a Common Rail injector is a crucial step to
suitably characterize the behaviour of an injector. The needle motion is traditionally …

Syringe filling of high-concentration mAb formulation: slow suck-back pump speed prevented filling needle clogging

S Hanslip, KG Desai, M Palmer, S Bell… - Journal of …, 2017 - Elsevier
Partial and complete clogging of filling needles occurred during syringe filling of a high-
concentration mAb formulation. This caused nonvertical liquid flow, which eventually led to …

Effect of Back-Cut Point Needle Bevel Angle on Deterioration After Multiple Punctures in Central Vein Simulation

G Urimoto, T Suzuki, M Matsuda, K Ito… - Medical Devices …, 2024 - Taylor & Francis
Background Multiple needle punctures during central venous line insertion can lead to
serious complications. Needle deterioration owing to repeated punctures may be a major …

Investigating liquid leak from pre-filled syringes upon needle shield removal: effect of air bubble pressure

E Chan, YF Maa, D Overcashier… - PDA Journal of …, 2011 - journal.pda.org
This study is to investigate the effect of headspace air pressure in pre-filled syringes on
liquid leak (dripping) from the syringe needle upon needle shield removal. Drip tests to …

A retractable winged steel (butterfly) needle performance improvement project

M Hotaling - Joint Commission Journal on Quality and …, 2009 - jointcommissionjournal.com
A Retractable Winged Steel (Butterfly) Needle Performance Improvement Project - Joint
Commission Journal on Quality and Patient Safety Skip to Main Content Skip to Main Menu …

Clogging in staked-in needle pre-filled syringes (SIN-PFS): Influence of water vapor transmission through the needle shield

M De Bardi, R Müller, C Grünzweig, D Mannes… - European Journal of …, 2018 - Elsevier
Staked-in needle pre-fillable syringes (SIN-PFS) are a convenient delivery system widely
established in the growing pharmaceutical market. Under specific storage conditions, the …