Monoclonal antibodies in cancer therapy
D Zahavi, L Weiner - Antibodies, 2020 - mdpi.com
Monoclonal antibody-based immunotherapy is now considered to be a main component of
cancer therapy, alongside surgery, radiation, and chemotherapy. Monoclonal antibodies …
cancer therapy, alongside surgery, radiation, and chemotherapy. Monoclonal antibodies …
Monoclonal antibodies for the treatment of cancer
CW Shuptrine, R Surana, LM Weiner - Seminars in cancer biology, 2012 - Elsevier
Over the past decade, the clinical utility of monoclonal antibodies has been realized and
antibodies are now a mainstay for the treatment of cancer. Antibodies have the unique …
antibodies are now a mainstay for the treatment of cancer. Antibodies have the unique …
Antibody therapy of cancer
AM Scott, JD Wolchok, LJ Old - Nature reviews cancer, 2012 - nature.com
The use of monoclonal antibodies (mAbs) for cancer therapy has achieved considerable
success in recent years. Antibody–drug conjugates are powerful new treatment options for …
success in recent years. Antibody–drug conjugates are powerful new treatment options for …
Monoclonal antibodies: versatile platforms for cancer immunotherapy
LM Weiner, R Surana, S Wang - Nature Reviews Immunology, 2010 - nature.com
Antibodies are important therapeutic agents for cancer. Recently, it has become clear that
antibodies possess several clinically relevant mechanisms of action. Many clinically useful …
antibodies possess several clinically relevant mechanisms of action. Many clinically useful …
Trial watch: Monoclonal antibodies in cancer therapy
E Vacchelli, A Eggermont, J Galon… - …, 2013 - Taylor & Francis
During the past 20 years, dozens—if not hundreds—of monoclonal antibodies have been
developed and characterized for their capacity to mediate antineoplastic effects, either as …
developed and characterized for their capacity to mediate antineoplastic effects, either as …
Trial Watch: Monoclonal antibodies in cancer therapy
L Galluzzi, E Vacchelli, WH Fridman, J Galon… - …, 2012 - Taylor & Francis
Since the advent of hybridoma technology, dating back to 1975, monoclonal antibodies
have become an irreplaceable diagnostic and therapeutic tool for a wide array of human …
have become an irreplaceable diagnostic and therapeutic tool for a wide array of human …
Improving the efficacy of antibody-based cancer therapies
P Carter - Nature Reviews Cancer, 2001 - nature.com
A quarter of a century after their advent, monoclonal antibodies have become the most
rapidly expanding class of pharmaceuticals for treating a wide variety of human diseases …
rapidly expanding class of pharmaceuticals for treating a wide variety of human diseases …
Building better magic bullets—improving unconjugated monoclonal antibody therapy for cancer
LM Weiner - Nature Reviews Cancer, 2007 - nature.com
The potential of monoclonal antibodies to effectively treat cancer is beginning to be widely
acknowledged. Advances in antibody engineering make it possible to produce various …
acknowledged. Advances in antibody engineering make it possible to produce various …
Monoclonal antibodies in cancer therapy
AM Scott, JP Allison, JD Wolchok - Cancer immunity, 2012 - AACR
Monoclonal antibody-based treatment of cancer has been established as one of the most
successful therapeutic strategies for both hematologic malignancies and solid tumors in the …
successful therapeutic strategies for both hematologic malignancies and solid tumors in the …
Monoclonal antibodies as immunomodulatory therapy against cancer and autoimmune diseases
U Hafeez, HK Gan, AM Scott - Current opinion in pharmacology, 2018 - Elsevier
Highlights•Monoclonal antibodies are effective treatment for various cancers and
autoimmune diseases.•Immune checkpoint therapy in cancer has emerged as a potent …
autoimmune diseases.•Immune checkpoint therapy in cancer has emerged as a potent …