Sound stress (SS) elicits behavioral changes, including pain behaviors. However, the
neuronal mechanisms underlying SS-induced pain behaviors remain to be explored. The …

Background Clinical studies demonstrated peripheral nociceptor deficit in stress‐related
chronic pain states, such as fibromyalgia. The interactions of stress and nociceptive systems …

Hyperalgesia is an exaggerated response to noxious stimuli produced by peripheral or
central plasticity. Stress modifies nociception, and humans with post-traumatic stress …

Background Reports show that stressful events before injury exacerbates post-injury pain.
The mechanism underlying stress-induced heightened thermal pain is unclear. Here, we …

While it is well established that acute stress can produce antinociception, a phenomenon
referred to as stress-induced analgesia, repeated exposure to stress can have the opposite …

Background Early-life stress and exposure to stressful stimuli play a major role in the
development of chronic widespread pain in adults. However, how they interact in chronic …

Corticotropin-releasing factor (CRF) plays a major role in controlling the body's response to
stress. Because painful conditions are inherently stressful, we hypothesize that CRF may act …

This study examines the contribution of central corticotropin-releasing factor (CRF) to pain
behavior. CRF is the principal modulator of the hypothalamo–pituitary–adrenal (HPA) axis …

In the military, constant physiological and psychological stress encountered by Soldiers can
lead to development of the combat and operational stress reaction (COSR), which can effect …

Repeated cold stress (RCS) can trigger the development of fibromyalgia (FM)-like
symptoms, including persistent deep-tissue pain, although nociceptive changes to the skin …