A review of antidiabetic active thiosugar sulfoniums, salacinol and neokotalanol, from plants of the genus Salacia

T Morikawa, K Ninomiya, G Tanabe, H Matsuda… - Journal of natural …, 2021 - Springer
During our studies characterizing functional substances from food resources for the
prevention and treatment of lifestyle-related diseases, we isolated the active constituents …

Antidiabetogenic constituents from Salacia species.

H Matsuda, M Yoshikawa, T Morikawa, G Tanabe… - 2005 - cabidigitallibrary.org
In the course of our studies on antidiabetogenic compounds from natural medicines and
medicinal foodstuffs, we found that the extracts from the roots and stems of Salacia …

Salacia chinensis stem extract and its thiosugar sulfonium constituent, neokotalanol, improves HbA1c levels in ob/ob mice

M Kobayashi, J Akaki, Y Yamaguchi… - Journal of natural …, 2019 - Springer
The antidiabetic effects of a hot water extract of the stems of Salacia chinensis (SCE) were
evaluated in vivo in ob/ob mice (genetically obese hyperglycemic mice). Administration of …

Anti‐diabetic and Anti‐hyperlipidemic Effects and Safety of Salacia reticulata and Related Species

SJ Stohs, S Ray - Phytotherapy Research, 2015 - Wiley Online Library
Extracts of Salacia reticulata Wight (Hypocrataceae) roots, stems, and leaves have been
used in Asia for hundreds of years for the folkloric treatment of diabetes and other health …

Salacinol and Related Analogs: New Leads for Type 2 Diabetes Therapeutic Candidates from the Thai Traditional Natural Medicine Salacia chinensis

T Morikawa, J Akaki, K Ninomiya, E Kinouchi… - Nutrients, 2015 - mdpi.com
The antidiabetic effect of a hot water extract of stems of Salacia chinensis (SCE) was
evaluated in vivo in KK-Ay mice, a typical type 2 diabetes mellitus mice model …

Salacia spp: hypoglycemic principles and possible role in diabetes management.

A Singh, S Duggal - Integrative Medicine: A Clinician's …, 2010 - search.ebscohost.com
The salacia species (Celastraceae), including S chinensis, S reticulata, and S oblonga, are
used as antidiabetic agents in traditional systems of medicine such as Ayurveda and Unani …

Evaluation of Salacia Species as Anti‐diabetic Natural Resources Based on Quantitative Analysis of Eight Sulphonium Constituents: A New Class of α‐Glucosidase …

J Akaki, T Morikawa, S Miyake… - Phytochemical …, 2014 - Wiley Online Library
Introduction Stems and roots of Salacia genus plants have been used in Ayurveda as a
specific remedy for early stage diabetes. Previous investigations identified four sulphonium …

Antidiabetogenic constituents from several natural medicines

H Matsuda, T Morikawa, M Yoshikawa - Pure and Applied Chemistry, 2002 - degruyter.com
In the course of our studies on antidiabetogenic and antidiabetic principles of natural
medicines and medicinal foodstuffs, we have isolated salacinol and kotalanol with unique …

Kotalanol, a potent α-glucosidase inhibitor with thiosugar sulfonium sulfate structure, from antidiabetic Ayurvedic medicine Salacia reticulata

M Yoshikawa, T Murakami, K Yashiro… - Chemical and …, 1998 - jstage.jst.go.jp
抄録 A potent natural α-glucosidase inhibitor called kotalanol has been isolated from an
antidiabetic traditional Ayurvedic medicine, the roots and stems of Salacia reticulata WIGHT …

Biological activities of Salacia chinensis originating in Thailand: the quality evaluation guided by alpha-glucosidase inhibitory activity

M Yoshikawa, Y Pongpiriyadacha, A Kishi… - … Zasshi: Journal of the …, 2003 - europepmc.org
In the course of our characterization studies on anti-obese and antidiabetogenic principles
in medicinal foodstuffs, we found that the methanolic extract from the stems of Salacia …