Nanoparticles used in cellular applications encounter free serum proteins that adsorb onto
the surface of the nanoparticle, forming a protein corona. This protein layer controls the …

The current understanding of nanoparticle–protein interactions indicates that they rapidly
adsorb proteins upon introduction into a living organism. The formed protein corona …

The use of nanocarriers in biology and medicine is complicated by the current need to
understand how nanoparticles interact in complex biological surroundings. When …

The surfaces of pristine nanoparticles become rapidly coated by proteins in biological fluids,
forming the so-called protein corona. The corona modifies key physicochemical …

Nanoparticles-based drug delivery systems have attracted significant attention in biomedical
fields because they can deliver loaded cargoes to the target site in a controlled manner …

The formation of a protein corona has been considered a pitfall in the clinical translation of
nanomedicines. Hence, interdisciplinary studies on corona characterization are critically …

In a physiological fluid (eg, blood), nanomaterials will strongly interact with proteins to form
“protein corona”. The structure and aggregation of protein corona around the nanoparticles …

Nanoparticle applications in biotechnology and biomedicine are steadily increasing. In
biological fluids, proteins bind to nanoparticles that form the protein corona, crucially …

In biological environments, nanoparticles are enshrouded by a layer of biomolecules,
predominantly proteins, mediating its subsequent interactions with cells. Detecting this …

Although a wide variety of nanoparticles (NPs) have been engineered for use as disease
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …