In broad terms,“advanced” heart failure describes a clinical syndrome characterized by
persistent or progressive symptoms and ventricular dysfunction despite guideline-directed …

Heart failure is a complex clinical syndrome resulting from impairment of ventricular filling or
ejection of blood associated with symptoms of dyspnea, fatigue, and peripheral and/or …

This article updates the Heart Failure Association of the European Society of Cardiology
(ESC) 2007 classification of advanced heart failure and describes new diagnostic and …

ContextAdvanced heart failure, defined as persistence of limiting symptoms despite therapy
with agents of proven efficacy, accounts for the majority of morbidity and mortality in heart …

BACKGROUND: A consensus conference was convened to define the current state and
important gaps in knowledge and needed research on “Palliative and Supportive Care in …

We propose that stage D advanced heart failure be defined as the presence of progressive
and/or persistent severe signs and symptoms of heart failure despite optimized medical …

Therapy has improved the survival of heart failure (HF) patients. However, many patients
progress to advanced chronic HF (ACHF). We propose a practical clinical definition and …

Chronic heart failure (CHF) is associated with a heavy burden of disease for patients and
healthcare professionals. Quality of life and long-term prognosis for affected patients remain …

Despite its high prevalence and significant rates of associated morbidity and mortality, the
syndrome of decompensated heart failure remains poorly defined and vastly understudied …

Heart failure remains a common diagnosis, especially in older individuals. It continues to be
associated with significant morbidity and mortality, but major advances in both diagnosis …