Normative intracranial EEG maps epileptogenic tissues in focal epilepsy

JM Bernabei, N Sinha, TC Arnold, E Conrad, I Ong… - Brain, 2022 - academic.oup.com
Planning surgery for patients with medically refractory epilepsy often requires recording
seizures using intracranial EEG. Quantitative measures derived from interictal intracranial …

Source-sink connectivity: A novel interictal EEG marker for seizure localization

KM Gunnarsdottir, A Li, RJ Smith, JY Kang… - Brain, 2022 - academic.oup.com
Over 15 million epilepsy patients worldwide have drug-resistant epilepsy. Successful
surgery is a standard of care treatment but can only be achieved through complete resection …

[HTML][HTML] High interictal connectivity within the resection zone is associated with favorable post-surgical outcomes in focal epilepsy patients

P Shah, JM Bernabei, LG Kini, A Ashourvan… - NeuroImage: Clinical, 2019 - Elsevier
Patients with drug-resistant focal epilepsy are often candidates for invasive surgical
therapies. In these patients, it is necessary to accurately localize seizure generators to …

Interictal intracranial electroencephalography for predicting surgical success: The importance of space and time

Y Wang, N Sinha, GM Schroeder, S Ramaraju… - …, 2020 - Wiley Online Library
Objective Predicting postoperative seizure freedom using functional correlation networks
derived from interictal intracranial electroencephalography (EEG) has shown some success …

Quantitative approaches to guide epilepsy surgery from intracranial EEG

JM Bernabei, A Li, AY Revell, RJ Smith… - Brain, 2023 - academic.oup.com
Over the past 10 years, the drive to improve outcomes from epilepsy surgery has stimulated
widespread interest in methods to quantitatively guide epilepsy surgery from intracranial …

Normative brain mapping of interictal intracranial EEG to localize epileptogenic tissue

PN Taylor, CA Papasavvas, TW Owen, GM Schroeder… - Brain, 2022 - academic.oup.com
The identification of abnormal electrographic activity is important in a wide range of
neurological disorders, including epilepsy for localizing epileptogenic tissue. However, this …

Using network analysis to localize the epileptogenic zone from invasive EEG recordings in intractable focal epilepsy

A Li, B Chennuri, S Subramanian, R Yaffe… - Network …, 2018 - direct.mit.edu
Abstract Treatment of medically intractable focal epilepsy (MIFE) by surgical resection of the
epileptogenic zone (EZ) is often effective provided the EZ can be reliably identified. Even …

Delineating epileptogenic networks using brain imaging data and personalized modeling in drug-resistant epilepsy

HE Wang, M Woodman, P Triebkorn… - Science Translational …, 2023 - science.org
Precise estimates of epileptogenic zone networks (EZNs) are crucial for planning
intervention strategies to treat drug-resistant focal epilepsy. Here, we present the virtual …

Virtual resection predicts surgical outcome for drug-resistant epilepsy

LG Kini, JM Bernabei, F Mikhail, P Hadar, P Shah… - Brain, 2019 - academic.oup.com
Patients with drug-resistant epilepsy often require surgery to become seizure-free. While
laser ablation and implantable stimulation devices have lowered the morbidity of these …

Integrating artificial intelligence with real-time intracranial EEG monitoring to automate interictal identification of seizure onset zones in focal epilepsy

Y Varatharajah, B Berry, J Cimbalnik… - Journal of neural …, 2018 - iopscience.iop.org
Objective. An ability to map seizure-generating brain tissue, ie the seizure onset zone (SOZ),
without recording actual seizures could reduce the duration of invasive EEG monitoring for …