Intervertebral disc degeneration (IVDD) is a pathological condition that can lead to
intractable back pain or secondary neurological deficits. There is no fundamental cure for …

Intervertebral disc (IVD) degeneration (IDD) is a multifactorial pathological process
associated with low back pain (LBP). The pathogenesis is complicated, and the main …

Intervertebral disc degeneration (IDD) causes a variety of signs and symptoms, such as low
back pain (LBP), intervertebral disc herniation, and spinal stenosis, which contribute to high …

Intervertebral disc degeneration (IDD) is the most common cause of low-back pain.
Accumulating evidence indicates that the expression profiling of noncoding RNAs (ncRNAs) …

Intervertebral disc degeneration is the primary cause of back pain and associated with
neurological disorders including radiculopathy, myelopathy, and paralysis. The currently …

Recent advances in surgical techniques have made it possible to study the changes that are
known as degeneration of the intervertebral disc (IVD) in greater depth than ever before …

Degeneration of intervertebral disc (IVD) is mainly a chronic process of excessive
destruction of the extracellular matrix (ECM), and also is thought to be the primary cause of …

Disc degeneration is the most common cause of back pain in adults and has enormous
socioeconomic implications. Conservative management is ineffective in most cases, and …

The underlying molecular mechanisms of intervertebral disc degeneration (IDD) remain
unclear. This study aimed to identify the crucial molecules and explore the function of …

Disc degeneration is the loss of the normal nucleus pulposus disc matrix to a more fibrotic
and less cartilaginous structure. This change in disc micro-anatomy can be associated with …