[HTML][HTML] Transcriptional Responses of Flavin-Containing Monooxygenase Genes in Scallops Exposed to PST-Producing Dinoflagellates Implying Their Involvements …

L Kong, P Liu, M Li, H Wang, J Shi, J Hu… - Frontiers in Marine …, 2021 - frontiersin.org
Flavin-containing monooxygenase (FMO) is one of the most prominent xenobiotic metabolic
enzymes. It can catalyze the conversion of heteroatom-containing chemicals to polar, readily …

Down-regulation of piscine flavin-containing mono-oxygenase activity by decreased salinity in euryhaline flounder (Platichthys flesus)

D Schlenk, LD Peters, DR Livingstone - Marine Environmental Research, 1996 - Elsevier
Flavin-containing mono-oxygenases (FMOs) play a significant role in xenobiotic
biotransformation in fish. However, endogenous functions of the enzyme have not been …

Effects of salinity acclimation on the pesticide-metabolizing enzyme flavin-containing monooxygenase (FMO) in rainbow trout (Oncorhynchus mykiss)

R Lavado, R Aparicio-Fabre, D Schlenk - Comparative Biochemistry and …, 2013 - Elsevier
Thioether-containing pesticides are more toxic in certain anadromous and catadromous fish
species that have undergone acclimation to hypersaline environments. Enhanced toxicity …

Unique monooxygenation pattern indicates novel flavin-containing monooxygenase in liver of rainbow trout

D Schlenk, C Yeung, A Rettie - Marine environmental research, 2004 - Elsevier
Vertebrate flavin-containing monooxygenases (FMOs) have only been isolated from
mammalian organisms. However, many FMO substrates include pesticides which may …

Developmental expression and regulation of flavin-containing monooxygenase by the unfolded protein response in Japanese medaka (Oryzias latipes)

A Kupsco, D Schlenk - Comparative Biochemistry and Physiology Part C …, 2017 - Elsevier
Flavin-containing monooxygenases (FMOs) play a key role in xenobiotic metabolism, are
regulated by environmental conditions, and are differentially regulated during mammalian …

Expression of branchial flavin-containing monooxygenase is directly correlated with salinity-induced aldicarb toxicity in the euryhaline fish (Oryzias latipes)

D Schlenk, A El-Alfy - Marine environmental research, 1998 - Elsevier
Earlier studies in our laboratory have demonstrated a reduction of flavin-containing
monooxygenase (FMO) activity when salt-water adapted euryhaline fish were transferred to …

Molecular identification and expression of two non-P450 enzymes, monoamine oxidase A and flavin-containing monooxygenase 2, involved in phase I of xenobiotic …

I Boutet, A Tanguy, D Moraga - Biochimica et Biophysica Acta (BBA)-Gene …, 2004 - Elsevier
Marine bivalve metabolism can be perturbed by hydrocarbon and pesticide pollution in
coastal ecosystems. In this study, in the Pacific oyster, Crassostrea gigas, full-length cDNAs …

Effect of cortisol and urea on flavin monooxygenase activity and expression in rainbow trout, Oncorhynchus mykiss

A El-Alfy, B Larsen, D Schlenk - Marine environmental research, 2002 - Elsevier
Expression of flavin-containing monooxygenase (s)(FMO) correlates with salinity exposure
in certain species of euryhaline fish, such as the rainbow trout, Oncorhynchus mykiss. The …

Differential expression and activity of flavin-containing monooxygenases in euryhaline and stenohaline flatfishes indicates potential osmoregulatory role

D Schlenk, L Peters, S Shehin-Johnson… - … and Physiology Part C …, 1995 - Elsevier
N, N-Dimethylaniline (DMA) N-oxidase activity indicative of flavin-containing
monooxygenase (FMO) was examined in four tissues (liver, gill, muscle, and kidney) of the …

Osmotic regulation of a novel flavin-containing monooxygenase in primary cultured cells from rainbow trout (Oncorhynchus mykiss)

G Rodríguez-Fuentes, R Aparicio-Fabre, Q Li… - Drug metabolism and …, 2008 - ASPET
A cDNA encoding a hepatic isoform of flavin-containing monooxygenase
(hFMO)(EF063736) containing an open reading frame of 1792 base pairs (bp) and encoding …