Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …

During tumor progression, circulating monocytes and macrophages are actively recruited
into tumors where they alter the tumor microenvironment to accelerate tumor progression …

In the past decade, substantial advances have been made in understanding the biology of
tumour-associated macrophages (TAMs), and their clinical relevance is emerging. A …

Macrophages, an important class of innate immune cells that maintain body homeostasis
and ward off foreign pathogens, exhibit a high degree of plasticity and play a supportive role …

Macrophages play an important role in tissue development and homeostasis. They serve as
a nexus between adaptive and innate immunity, and employ considerable plasticity. In …

Macrophages are heterogeneous cells that present as different functional phenotypes due to
their plasticity. They can be classified into two categories, namely M1-and M2-like …

Inflammation is now a well-recognized hallmark of cancer progression. Tumor-associated
macrophages (TAMs) are one of the major inflammatory cells that infiltrate murine and …

The fact that various immune cells, including macrophages, can be found in tumor tissues
has long been known. With the introduction of concept that macrophages differentiate into a …

Long recognized as an evolutionarily ancient cell type involved in tissue homeostasis and
immune defense against pathogens, macrophages are being re-discovered as regulators of …

Tumor-associated macrophages (TAM) are key regulators of the link between inflammation
and cancer. In the tumor microenvironment neoplastic cells shape the differentiation and …