Chemical design and synthesis of functionalized probes for imaging and treating tumor hypoxia
Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …
strong resistance to therapy, leading to the poor prognosis in several cancer types …
Designing Hypoxia‐Responsive Nanotheranostic Agents for Tumor Imaging and Therapy
H Zhou, F Qin, C Chen - Advanced Healthcare Materials, 2021 - Wiley Online Library
Hypoxia, a common feature of most solid tumors, plays an important role in tumor
proliferation, metastasis, and invasion, leading to drug, radiation, and photodynamic therapy …
proliferation, metastasis, and invasion, leading to drug, radiation, and photodynamic therapy …
Modulating hypoxia via nanomaterials chemistry for efficient treatment of solid tumors
Y Liu, Y Jiang, M Zhang, Z Tang, M He… - Accounts of Chemical …, 2018 - ACS Publications
Conspectus The common existence of hypoxia in solid tumors has been heavily researched
because it renders tumors more resistant to most standard therapeutic methods, such as …
because it renders tumors more resistant to most standard therapeutic methods, such as …
Nano versus molecular: Optical imaging approaches to detect and monitor tumor hypoxia
Hypoxia is a ubiquitous feature of solid tumors, which plays a key role in tumor angiogenesis
and resistance development. Conventional hypoxia detection methods lack continuous …
and resistance development. Conventional hypoxia detection methods lack continuous …
Hypoxia-responsive nanocarriers for cancer imaging and therapy: recent approaches and future perspectives
Hypoxia, a condition in which the tissue is deprived of adequate oxygen supply, is a salient
feature of various intractable diseases, including rheumatoid arthritis, ischemic stroke, and …
feature of various intractable diseases, including rheumatoid arthritis, ischemic stroke, and …
Nanomedicine strategies in conquering and utilizing the cancer hypoxia environment
Y Pan, L Liu, X Mou, Y Cai - ACS nano, 2023 - ACS Publications
Cancer with a complex pathological process is a major disease to human welfare. Due to
the imbalance between oxygen (O2) supply and consumption, hypoxia is a natural …
the imbalance between oxygen (O2) supply and consumption, hypoxia is a natural …
A new strategy toward “simple” water‐soluble AIE probes for hypoxia detection
Hypoxia‐responsive fluorescent probes have emerged as a novel scaffold for tumor
diagnosis. However, dilemma often exists between simple synthesis and high water …
diagnosis. However, dilemma often exists between simple synthesis and high water …
Hypoxia-triggered self-assembly of ultrasmall iron oxide nanoparticles to amplify the imaging signal of a tumor
H Zhou, M Guo, J Li, F Qin, Y Wang, T Liu… - Journal of the …, 2021 - ACS Publications
Hypoxia is a common phenomenon among most solid tumors that significantly influences
tumor response toward chemo-and radiotherapy. Understanding the distribution and extent …
tumor response toward chemo-and radiotherapy. Understanding the distribution and extent …
Advanced nanomaterials for hypoxia tumor therapy: challenges and solutions
In recent years, nanomaterials and nanotechnology have emerged as vital factors in the
medical field with a unique contribution to cancer medicine. Given the increasing number of …
medical field with a unique contribution to cancer medicine. Given the increasing number of …
Hypoxia-active nanoparticles used in tumor theranostic
Hypoxia is a hallmark of malignant tumors and often correlates with increasing tumor
aggressiveness and poor treatment outcomes. Therefore, early diagnosis and effective …
aggressiveness and poor treatment outcomes. Therefore, early diagnosis and effective …