Vascularization, the formation of new blood vessels, is an essential biological process. As
the vasculature is involved in various fundamental physiological phenomena and closely …

Microphysiological systems have emerged in the last decade to provide an alternative to in
vivo models in basic science and pharmaceutical research. In the field of vascular biology, in …

Neovascularization, the formation of new blood vessels, has received much research
attention due to its implications for physiological processes and diseases. Most studies …

Highlights•Several viable methods currently exist to create vascularized in vitro
tissues.•Progress has been made in developing systems that mimic specific organs or …

Microfluidic technology has been extensively employed in biology and medicine since the
field emerged in the 1990s. By utilizing microfluidic approaches, a variety of vascular system …

Microfluidics is invaluable for studying microvasculature, development of organ-on-chip
models and engineering microtissues. Microfluidic design can cleverly control geometry …

The development of Vasculature-on-Chip has progressed rapidly over the last decade and
recently, a wealth of fabrication possibilities has emerged that can be used for engineering …

Reconstruction of 3D vascularized microtissues within microfabricated devices has rapidly
developed in biomedical engineering, which can better mimic the tissue microphysiological …

Vascular diseases, such as atherosclerosis and thrombosis, are major causes of morbidity
and mortality worldwide. Traditional in vitro models for studying vascular diseases have …

Hydrogel structures equipped with internal microchannels offer more in vivo‐relevant
models for construction of tissues and organs in vitro. However, currently used …