[HTML][HTML] Role of apigenin in cancer prevention via the induction of apoptosis and autophagy

B Sung, HY Chung, ND Kim - Journal of cancer prevention, 2016 - ncbi.nlm.nih.gov
Abstract Apigenin (4′, 5, 7-trihydroxyflavone) is a flavonoid commonly found in many fruits
and vegetables such as parsley, chamomile, celery, and kumquats. In the last few decades …

Apigenin's anticancer properties and molecular mechanisms of action: Recent advances and future prospectives

JMM Salmani, XP Zhang, JA Jacob… - Chinese journal of natural …, 2017 - Elsevier
Cancer is a major health concern and leading burden on economy worldwide. An increasing
effort is devoted to isolation and development of plant-derived dietary components as …

Role of induced programmed cell death in the chemopreventive potential of apigenin

JY Jang, B Sung, ND Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
The flavonoid apigenin (4′, 5, 7-trihydroxyflavone), which is one of the most widely
distributed phytochemicals in the plant kingdom, is one of the most thoroughly investigated …

Apigenin and cancer chemoprevention: progress, potential and promise

D Patel, S Shukla, S Gupta - … journal of oncology, 2007 - spandidos-publications.com
Cancer is one of the major public health burdens in the United States and in other
developed countries, causing approximately 7 million deaths every year worldwide. Cancer …

Apigenin-induced apoptosis is enhanced by inhibition of autophagy formation in HCT116 human colon cancer cells

Y Lee, B Sung, YJ Kang, DH Kim… - International …, 2014 - spandidos-publications.com
Abstract Apigenin (4', 5, 7-trihydroxyflavone) is a natural flavonoid, shown to have
chemopreventive and/or anticancer properties in a variety of human cancer cells. The …

[HTML][HTML] Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells

J Yang, C Pi, G Wang - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Apigenin is a dietary flavonoid with known antioxidant and antitumor effects against several
types of cancers by promoting cell death and inducing cell cycle arrest. Apigenin also …

Apigenin induces cell cycle arrest and p21/WAF1 expression in a p53-independent pathway

N Takagaki, Y Sowa, T Oki… - International …, 2005 - spandidos-publications.com
Apigenin, a common dietary flavonoid, has been shown to induce cell growth-inhibition and
cell cycle arrest in many cancer cell lines. One important effect of apigenin is to increase the …

Inhibition of MDA‐MB‐231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation‐mediated …

TH Tseng, MH Chien, WL Lin, YC Wen… - Environmental …, 2017 - Wiley Online Library
ABSTRACT Apigenin (4′, 5, 7‐trihydroxyflavone), a flavonoid commonly found in fruits and
vegetables, has anticancer properties in various malignant cancer cells. However, the …

Apigenin role as cell-signaling pathways modulator: implications in cancer prevention and treatment

Z Javed, H Sadia, MJ Iqbal, S Shamas, K Malik… - Cancer Cell …, 2021 - Springer
Cancer is a complex disease orchestrated by various extrinsic and intrinsic pathways. In
recent years, there has been a keen interest towards the development of natural extracts …

Apigenin induces apoptosis in human lung cancer H460 cells through caspase-and mitochondria-dependent pathways

HF Lu, YJ Chie, MS Yang, KW Lu… - Human & …, 2011 - journals.sagepub.com
Apigenin (4, 5, 7-trihydroxyflavone), a promising chemopreventive agent presented in fruits
and vegetables, has been shown to induce cell cycle arrest and apoptosis in many types of …