Studies were designed to examine the regulation of apolipoprotein (apo) AI gene
expression in Cu-depleted Hep G2 cells. The cupruretic chelator N, N′-bis (2-aminoethyl) …

Two amine chelators, namely N, N′-bis (2-aminoethyl)-1, 3-propanediamine-4 HCl (2, 3, 2-
tetramine) and diamsar, were used at various levels to deplete copper (Cu) from cultured …

This study was designed to determine whether an increase in hepatic apolipoprotein AI (apo
AI) synthesis and mRNA abundance is responsible for the enlarged plasma apo AI pool …

Forty-eight male weanling Sprague-Dawley rats were randomly assigned to two dietary
treatments, copper-deficient (CD) and copper-adequate (CA). After 6 weeks, rats were …

The influence of Zn on the expression of the apolipoprotein AI (apoA-I) gene in Hep G2 cells
was examined. Zn depletion was achieved with a low-Zn (ZD) medium prepared from Zn …

This study was designed to determine whether an enhanced intestinal synthesis of
apolipoprotein (apo) AI is associated with the hyperapolipoproteinemia observed in copper …

The influence of Zn deficiency on the plasma level as well as the hepatic and intestinal gene
expression of apolipoprotein (apo) AI was examined in rats and hamsters. Male Sprague …

Previously published studies suggest that an alteration in hexosamine flux induces a state of
insulin resistance in muscle, liver, and other cell types. Glucosamine also alters the …

Male weanling Sprague-Dawley rats were assigned to copper-deficient (9.0 mumol Cu/kg
diet) or copper-adequate (102 mumol Cu/kg diet) dietary treatments for 6 wk. Pulse-chase …

Copper deficiency induces hypercholesterolemia in the rat. This hypercholesterolemia is
mainly due to an increase in apo E-rich high density lipoproteins (HDL 1). The present study …