Voltage-gated potassium (Kv) channels mediate rapid, selective diffusion of K+ ions through
the plasma membrane, controlling cell excitability, secretion and signal transduction. KCNE …

Voltage-gated potassium channels provide tightly Controlled, ion-specific pathways across
membranes and are key to the normal function of nerves muscles. They arise from the …

1. INTRODUCTION 3581.1 Summary 3581.2 Overview 3591.3 Four classes of pore-forming
K+ channel subunits–necessary and (sometimes) sufficient 3611.4 Soluble and peripheral …

Delayed rectifier potassium current diversity and regulation are essential for signal
processing and integration in neuronal circuits. Here, we investigated a neuronal role for …

KCNE genes encode single transmembrane-domain subunits, the MinK-related peptides
(MiRPs), which assemble with pore-forming alpha subunits to establish the attributes of …

Abstract Kv2. 1 is a voltage-gated potassium (Kv) channel α-subunit expressed in
mammalian heart and brain. MinK-related peptides (MiRPs), encoded by KCNE genes, are …

Voltage-gated potassium (Kv) channels extend their functional repertoire by coassembling
with MinK-related peptides (MiRPs). MinK slows the activation of channels formed with …

MinK-related peptides (MiRPs) are single transmembrane proteins that associate with
mammalian voltage-gated K+ subunits. Here we report the cloning and functional …

The HCN family of ion channel subunits underlies the currents I f in heart and I h and I q in
the nervous system. In the present study, we demonstrate that minK-related peptide 1 …

High frequency firing in mammalian neurons requires ultra-rapid delayed rectifier potassium
currents generated by homomeric or heteromeric assemblies of Kv3. 1 and Kv3. 2 potassium …