Assessing pulmonary ventilation and perfusion properties with 19F-MRI

BJ Pippard - 2021 - theses.ncl.ac.uk
Pulmonary imaging with conventional MRI remains challenging, owing to the low proton
density of lung tissue and magnetic susceptibility gradients that exist at ubiquitous air-tissue …

P137 19 f-mri of inhaled perfluoropropane gas: a novel approach to ventilation imaging

B Pippard, M Neal, P Dutta, AJ Simpson, P Thelwall - 2017 - thorax.bmj.com
Introduction Current measures of pulmonary ventilation are beset by limitations. For
example, spirometry provides no regional or anatomical information regarding lung function …

Assessing regional lung ventilation with 19F-MRI of inhaled perfluoropropane

B Pippard, M Neal, A Maunder, I Forrest, I Sabroe… - 2018 - Eur Respiratory Soc
Background: 19 F-MRI of inhaled perfluoropropane (PFP) has recently emerged as a viable
approach to ventilation imaging, offering an alternative to hyperpolarised gas MRI. Aim: We …

19F MRI of the Lungs Using Inert Fluorinated Gases: Challenges and New Developments

MJ Couch, IK Ball, T Li, MS Fox… - Journal of Magnetic …, 2019 - Wiley Online Library
Fluorine‐19 (19F) MRI using inhaled inert fluorinated gases is an emerging technique that
can provide functional images of the lungs. Inert fluorinated gases are nontoxic, abundant …

Inert fluorinated gas MRI: a new pulmonary imaging modality

MJ Couch, IK Ball, T Li, MS Fox… - NMR in …, 2014 - Wiley Online Library
Fluorine‐19 (19F) MRI of the lungs using inhaled inert fluorinated gases can potentially
provide high quality images of the lungs that are similar in quality to those from …

[HTML][HTML] Quantification of pulmonary functional MRI: state-of-the-art and emerging image processing methods and measurements

M Sharma, PV Wyszkiewicz… - Physics in Medicine …, 2022 - iopscience.iop.org
Pulmonary functional magnetic resonance imaging (PfMRI) provides a way to non-invasively
map and measure the spatial distribution of pulmonary ventilation, perfusion and gas …

S68 Assessing pulmonary ventilation and treatment response in patients with asthma and COPD using 19F-MRI: results from the LIFT study

C Holland, M Neal, B Pippard, I Forrest, G Burns… - 2022 - thorax.bmj.com
Introduction Pulmonary ventilation reflects lung physiology, offering insight regarding
structural and functional changes associated with respiratory disease. However, in routine …

A 3D printed lung phantom for exploration of the limits of 19 FC 3 F 8 ventilation imaging resolution and SNR

A Maunder, F Robb, M Rao, J Wild - archive.ismrm.org
Fluorinated gas imaging is a complementary method to hyperpolarized gas ventilation
imaging, but suffers from lower SNR by virtue of low spin density and thermal polarisation …

Comparison of Discrete Acquisition Techniques for Measuring Fractional Ventilation Using Hyperpolarized 129Xe MRI

L Loza, TS Achekzai, S Kadlecek… - B64. NEW INSIGHTS …, 2022 - atsjournals.org
RATIONALE We explored the effects of two different wash-out gases on fractional ventilation
(FV) measurements obtained using a wash-in/wash-out (wIwO) imaging scheme for …

¹⁹F-MRI of inhaled perfluoropropane for quantitative imaging of pulmonary ventilation

MA Neal - 2017 - theses.ncl.ac.uk
MRI of exogenous imaging agents offers a safely repeatable modality to assess regional
pulmonary ventilation. A small number of studies have validated the safety and potential …