Due to its poor prognosis and the late stage at which it is typically diagnosed, early detection
of pancreatic cancer is a pressing clinical problem. Advances in genomic analysis of human …

By genomic and epigenomic screening techniques, substantial progress has been made in
our understanding of pancreatic cancer. The comprehensive studies of the pancreatic …

Pancreatic cancer is the fourth leading cause of cancer death in men and women;
approximately 28,000 patients are diagnosed with pancreatic cancer and approximately …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers worldwide.
Despite significant progresses in the last decades, the origin of this cancer remains unclear …

Pancreatic cancer is the deadliest of all solid malignancies. Early detection offers the best
hope for a cure, but characteristics of this disease, such as the lack of early clinical …

Pancreatic cancer is the fourth most common cause of cancer death in the United States.
There is a great need for better diagnostic markers of pancreatic neoplasia. Better markers …

Context.—The introduction of genome-and epigenome-wide screening techniques has
dramatically improved our understanding of the molecular mechanisms underlying the …

Pancreatic cancer arises from noninvasive precursor lesions, including pancreatic
intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and …

Pancreatic cancer is an aggressive disease with a dismal prognosis in dire need of novel
diagnostic and therapeutic approaches. The past decade has witnessed an explosion of …

Pancreatic cancer is a genetic disease. Pancreatic cancers develop from one of three
precursor lesions, pancreatic intraepithelial neoplasia (PanIN), intraductal papillary …