Adipose tissue is one of the main sources of inflammatory mediators, with interleukin-6 (IL-6)
among them. Although high systemic levels of inflammatory mediators are cachectogenic …

Interleukin (IL)-6 is a pleotropic cytokine with various physiological and pathophysiological
functions in different cells and tissues. In cells residing within white adipose tissue, several …

Objective: To elucidate the hormonal regulation of interleukin-6 (IL-6) production by human
adipose tissue and its relation to leptin. Design: In vitro study. Human adipocytes were …

A variety of cytokines and other compounds are produced in the human adipose tissue and
may have autocrine functions in the adipose tissue as well as be involved in the …

Obesity is associated with the increased risk of cardiovascular disease; however,
mechanisms responsible for such an increase are not fully understood. IL-8 is a cytokine that …

Chronic low‐grade inflammation has been well recognized as a key feature of obesity that is
correlated with insulin resistance and type 2 diabetes. Among the adipose‐secreted factors …

Summary Interleukin‐6 (IL‐6) is a central player in the regulation of inflammation,
haematopoiesis, immune response and host defense mechanisms. During the last decade …

Inflammation plays a major role in the development of chronic diseases such as
cardiovascular disease and Type 2 diabetes. Further, it was demonstrated that obese …

Obesity is associated with a chronic state of low-grade inflammation and progressive tissue
infiltration by immune cells and increased expression of inflammatory cytokines. It is …

Advances in adipose tissue biology over the past 10 years have led to an improved
understanding of the mechanisms linking obesity with the metabolic syndrome and other …