Branched chain amino acids—friend or foe in the control of energy substrate turnover and insulin sensitivity?

E Supruniuk, E Żebrowska… - Critical Reviews in Food …, 2023 - Taylor & Francis
Branched chain amino acids (BCAA) and their derivatives are bioactive molecules with
pleiotropic functions in the human body. Elevated fasting blood BCAA concentrations are …

[HTML][HTML] Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 …

F Vanweert, P Schrauwen, E Phielix - Nutrition & diabetes, 2022 - nature.com
Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging
role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D) …

BCAA metabolism and insulin sensitivity–Dysregulated by metabolic status?

NP Gannon, JK Schnuck… - Molecular nutrition & food …, 2018 - Wiley Online Library
Branched‐chain amino acids (BCAAs) appear to influence several synthetic and catabolic
cellular signaling cascades leading to altered phenotypes in mammals. BCAAs are most …

[HTML][HTML] A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

CB Newgard, J An, JR Bain, MJ Muehlbauer… - Cell metabolism, 2009 - cell.com
Metabolomic profiling of obese versus lean humans reveals a branched-chain amino acid
(BCAA)-related metabolite signature that is suggestive of increased catabolism of BCAA and …

Branched‐chain amino acids differently modulate catabolic and anabolic states in mammals: a pharmacological point of view

F Bifari, E Nisoli - British journal of pharmacology, 2017 - Wiley Online Library
Substantial evidence has been accumulated suggesting that branched‐chain amino acid
(BCAA) supplementation or BCAA‐rich diets have a positive effect on the regulation of body …

[HTML][HTML] Branched-chain amino acids in health and disease: metabolism, alterations in blood plasma, and as supplements

M Holeček - Nutrition & metabolism, 2018 - Springer
Branched-chain amino acids (BCAAs; valine, leucine, and isoleucine) are essential amino
acids with protein anabolic properties, which have been studied in a number of muscle …

[HTML][HTML] Branched-chain amino acids and insulin resistance, from protein supply to diet-induced obesity

JP De Bandt, X Coumoul, R Barouki - Nutrients, 2022 - mdpi.com
For more than a decade, there has been a wide debate about the branched-chain amino
acids (BCAA) leucine, valine, and isoleucine, with, on the one hand, the supporters of their …

[HTML][HTML] Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state

SH Adams - Advances in nutrition, 2011 - Elsevier
Dysregulation of insulin action is most often considered in the context of impaired glucose
homeostasis, with the defining feature of diabetes mellitus being elevated blood glucose …

Branched-chain amino acids as biomarkers in diabetes

P Giesbertz, H Daniel - Current Opinion in Clinical Nutrition & …, 2016 - journals.lww.com
Branched-chain amino acids as biomarkers in diabetes : Current Opinion in Clinical Nutrition &
Metabolic Care Branched-chain amino acids as biomarkers in diabetes : Current Opinion in …

[HTML][HTML] Recent progress on branched-chain amino acids in obesity, diabetes, and beyond

MAB Siddik, AC Shin - Endocrinology and Metabolism, 2019 - synapse.koreamed.org
Branched-chain amino acids (BCAAs) are essential amino acids that are not synthesized in
our body; thus, they need to be obtained from food. They have shown to provide many …