Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer.
LW Harries, MJ Stubbins, D Forman… - …, 1997 - academic.oup.com
Two variant glutathione S-transferase cDNAs have been described at the GSTP1 locus,
which differ by a single base pair (AG) substitution at nucleotide 313 of the GSTP1 cDNA …
which differ by a single base pair (AG) substitution at nucleotide 313 of the GSTP1 cDNA …
Glutathione transferase isozyme genotypes in patients with prostate and bladder carcinoma
C Steinhoff, KH Franke, K Golka, R Thier… - Archives of …, 2000 - Springer
Genotype distributions for GSTP1, GSTM1, and GSTT1 were determined in 91 patients with
prostatic carcinoma and 135 patients with bladder carcinoma and compared with those in …
prostatic carcinoma and 135 patients with bladder carcinoma and compared with those in …
Polymorphism of the Pi class glutathione S-transferase in normal populations and cancer patients
MJ Harris, M Coggan, L Langton… - Pharmacogenetics …, 1998 - journals.lww.com
Deficiencies of the glutathione transferase isoenzymes GSTM1-1 and GSTT1-1 have been
shown to be risk modifiers in a number of different cancers but there have been no similar …
shown to be risk modifiers in a number of different cancers but there have been no similar …
Polymorphisms of glutathione‐S‐transferase genes (GSTP1, GSTM1 and GSTT1) and prostate‐cancer risk
A Gsur, G Haidinger, S Hinteregger… - … journal of cancer, 2001 - Wiley Online Library
Several polymorphic glutathione‐S‐transferase (GST) enzymes are involved in the
metabolism of a number of potential prostate carcinogens and are thought to engage in the …
metabolism of a number of potential prostate carcinogens and are thought to engage in the …
Genetic polymorphism of glutathione S-transferases M1 and T1 as a risk factor in lung and bladder cancers.
J Salagovic, I Kalina, J Stubna, V Habalova, M Hrivnak… - Neoplasma, 1998 - europepmc.org
A combined analysis of two polymorphic enzymes, glutathione S-transferase mu (GST M1)
and q (GST T1) and their implication as cancer risk factors was performed in a case-control …
and q (GST T1) and their implication as cancer risk factors was performed in a case-control …
Relationship between glutathione S-transferase M1, P1 and T1 polymorphisms and early onset prostate cancer
Z Kote-Jarai, D Easton, SM Edwards… - Pharmacogenetics …, 2001 - journals.lww.com
There is evidence suggesting that polymorphic variations in the glutathione S-transferases
(GSTs) are associated with cancer susceptibility. Inter-individual differences in cancer …
(GSTs) are associated with cancer susceptibility. Inter-individual differences in cancer …
Human glutathione S-transferase P1 polymorphism and susceptibility to smoking related epithelial cancer; oral, lung, gastric, colorectal and urothelial cancer
T Katoh, S Kaneko, S Takasawa… - Pharmacogenetics …, 1999 - journals.lww.com
The A/G polymorphism at nucleotide 313 in the glutathione S-transferase P1-1 (GSTP1)
gene was examined in patients with different types of smoking-related cancers (oral, lung …
gene was examined in patients with different types of smoking-related cancers (oral, lung …
Cytochrome P4501A1 gene polymorphism and homozygous deletion of the glutathione S-transferase M1 gene in urothelial cancer patients
T Katoh, H Inatomi, A Nagaoka, A Sugita - Carcinogenesis, 1995 - academic.oup.com
Japanese urothelial (bladder, renal pelvis and ureter) cancer patients (n= 83) and
community controls (n= 101) were compared for rates of polymorphism in exon 7 of the …
community controls (n= 101) were compared for rates of polymorphism in exon 7 of the …
I105V Polymorphism and Promoter Methylation of the GSTP1 Gene in Prostate Adenocarcinoma
The GSTP1 gene encodes for an enzyme, glutathione S-transferase π (GSTπ), involved in
detoxification of carcinogens. An aminoacid substitution (I105V) in GSTP1 produces a …
detoxification of carcinogens. An aminoacid substitution (I105V) in GSTP1 produces a …
Association of genetic polymorphism of glutathione S-transferase (GSTM1, GSTT1, GSTP1) with bladder cancer susceptibility
MR Safarinejad, S Safarinejad, N Shafiei… - … oncology: Seminars and …, 2013 - Elsevier
The glutathione-S-transferases (GSTs) comprise a class of enzymes that detoxify
carcinogenic compounds by conjugating glutathione to facilitate their removal …
carcinogenic compounds by conjugating glutathione to facilitate their removal …
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