[HTML][HTML] Therapeutic potential of Coptis chinensis for arthritis with underlying mechanisms

M Li, F Tian, J Guo, X Li, L Ma, M Jiang… - Frontiers in …, 2023 - frontiersin.org
Arthritis is a common degenerative disease of joints, which has become a public health
problem affecting human health, but its pathogenesis is complex and cannot be eradicated …

Shang-Ke-Huang-Shui and coptisine alleviate osteoarthritis in the knee of monosodium iodoacetate-induced rats through inhibiting CXCR4 signaling

K Yang, Q Xie, J Liao, N Zhao, J Liang, B Liu… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Shang-Ke-Huang-Shui (SKHS) is a classic
traditional Chinese medicine formula originally from the southern China city of Foshan. It has …

Clematichinenoside AR inhibits the pathology of rheumatoid arthritis by blocking the circPTN/miR-145-5p/FZD4 signal axis

X Wang, D Zhou, W Zhou, J Liu, Q Xue, Y Huang… - International …, 2022 - Elsevier
Abstract Backgrounds Traditional Chinese medicine roots and rhizomes of Clematis
chinensis Osbeck (CCO) has the effect of improving rheumatoid arthritis (RA) …

[HTML][HTML] Network pharmacology and molecular docking to elucidate the potential mechanism of ligusticum chuanxiong against osteoarthritis

C Xiang, Y Liao, Z Chen, B Xiao, Z Zhao, A Li… - Frontiers in …, 2022 - frontiersin.org
Background: Osteoarthritis (OA) is a degenerative disease which serious affects patients.
Ligusticum chuanxiong (CX) has been shown to have a certain curative effect on …

Identification of JUN as determinant of osteoarthritis and its inhibition by the Chinese herbal formulae Zhuanggu Huoxue Tang

Z Zheng, M Guo, W Zhu, W Cheng, L Kong, Y Liu… - Computers in Biology …, 2022 - Elsevier
Synovitis is an essential feature of Osteoarthritis (OA). Increasing evidence demonstrates
that synovitis plays a critical role in OA's symptoms and structural progression. However …

Exploring the chondroprotective effect of Chaenomeles speciosa on Glucose-6-Phosphate Isomerase model mice using an integrated approach of network …

Z Duan, C Jin, Y Deng, J Liu, C Gu, J Wang… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Traditional Chinese medicine (TCM) has been
used in China for a long time and is gradually gaining more and more recognition …

Coptisine inhibits aggressive and proliferative actions of fibroblast like synoviocytes and exerts a therapeutic potential for rheumatoid arthritis

F Xu, C Shen, S Zhang, Y Liu, D Liu, Y Kuang… - International …, 2024 - Elsevier
Objective Coptisine, a natural bioactive small molecular compound extracted from traditional
Chinese herb Coptis chinensis, has been shown to exhibit anti-tumor effect. However, its …

Pinocembrin reduces arthritic symptoms in mouse model via targeting Sox4 signaling molecules

EA Ahmed, HIM Ibrahim, HE Khalil - Journal of Medicinal Food, 2021 - liebertpub.com
Rheumatoid arthritis (RA) is a chronic autoimmune, multifactorial, inflammatory disorder
characterized by hyperplasia and infiltration of inflammatory cells at the synovial lining …

Isolation and Identification of Antiarthritic Constituents from Glycine tabacina and Network Pharmacology-Based Prediction of Their Protective Mechanisms against …

Y Tu, K Wang, X Jia, L Tan, B Han… - Journal of Agricultural …, 2020 - ACS Publications
Glycine tabacina (Labill.) Benth is an edible medicinal herb for rheumatoid arthritis (RA)
treatment in folk medicine. Current phytochemical research on this dried herb led to the …

Discovery and validation of anti-arthritic ingredients and mechanisms of Qingfu Juanbi Tang, a Chinese herbal formulation, on rheumatoid arthritis

M Peng, Z Yao, J Zhang, Y Lin, L Xu, Q Zhang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Qingfu Juanbi Tang (QFJBT), a novel and
improved Chinese herbal formulation, has surged in recent years for its potential in the …