Male germ cell apoptosis: regulation and biology

C Shaha, R Tripathi, DP Mishra - … Transactions of the …, 2010 - royalsocietypublishing.org
Cellular apoptosis appears to be a constant feature in the adult testis and during early
development. This is essential because mammalian spermatogenesis is a complex process …

A matter of death and life: the significance of germ cell death during spermatogenesis.

J Blanco-Rodriguez - International journal of andrology, 1998 - europepmc.org
The significance of cell death occurring during spermatogenesis is a subject of interest
because of its potential medical importance. Unfortunately, the field has been difficult for …

Testicular leukocytes: what are they doing?

MP Hedger - Reviews of reproduction, 1997 - rep.bioscientifica.com
Programmed cell death is an evolutionarily conserved cell death process that plays a major
role during normal development and homeostasis. In many cases, the ordered execution of …

Male germ cell development: turning on the apoptotic pathways

R Tripathi, DP Mishra, C Shaha - Journal of reproductive immunology, 2009 - Elsevier
From the viewpoint of improving germ cell production and treatment of testicular cancers,
understanding the control of testicular cell death is of great relevance. One of the prominent …

Hormonal and genetic control of germ cell apoptosis in the testis

APS Hikim, RS Swerdloff - Rev Reprod, 1999 - rep.bioscientifica.com
Programmed cell death is an evolutionarily conserved cell death process that plays a major
role during normal development and homeostasis. In many cases, the ordered execution of …

Deciphering the pathways of germ cell apoptosis in the testis

APS Hikim, Y Lue, M Diaz-Romero, PH Yen… - The Journal of steroid …, 2003 - Elsevier
A growing body of evidence demonstrates that germ cell death both spontaneous (during
normal spermatogenesis) and that induced by suppression of hormonal support or …

Programmed cell death in the germline

JS Baum, JPS George, K McCall - Seminars in Cell & Developmental …, 2005 - Elsevier
In many organisms, programmed cell death of germ cells is required for normal
development. This often occurs through highly conserved events including the transfer of …

Apoptosis in the germ line

RJ Aitken, JK Findlay, KJ Hutt, JB Kerr - Reproduction, 2011 - rep.bioscientifica.com
Apoptosis is a critical process for regulating both the size and the quality of the male and
female germ lines. In this review, we examine the importance of this process during …

Autonomous cell death of mouse male germ cells during fetal and postnatal period

RA Wang, PK Nakane, T Koji - Biology of reproduction, 1998 - academic.oup.com
Germ cell degeneration is common in mammalian testes during the developmental as well
as the adult period. To investigate the extent and mechanisms of male germ cell death …

Germ cell suicide: new insights into apoptosis during spermatogenesis

CG Print, KL Loveland - Bioessays, 2000 - Wiley Online Library
Mature sperm are the product of a precisely regulated developmental sequence in which
germ cell proliferation, differentiation, self‐renewal and apoptosis are carefully controlled …