Using bone tissue engineering strategies to achieve bone defect repair is a promising
modality. However, the repair process outcomes are often unsatisfactory. Here we properly …

Bone tissue repair is influenced by the synergistic interaction between acute immune
microenvironment and osteogenesis. In this study will be independently by film dispersion …

Various types of biomaterials have been widely used to treat complex bone defects.
However, potential infection risks and inappropriate host immune responses induced by …

Organic/inorganic composites have advantages in promoting bone repair; however, early
changes in the local immune response after material implantation and the mechanisms that …

In order to repair critical‐sized bone defects, various polylactic acid‐glycolic acid (PLGA)‐
based hybrid scaffolds are successfully developed as bone substitutes. However, the …

Abstract The 'clean-to-repair'rhythm in the dynamic pathological osteoimmune
microenvironment is essential to bone healing but often disturbed by the intense …

The immune microenvironment plays a vital role in bone defect repair. To create an immune
microenvironment that promotes osteogenesis, researchers are exploring ways to enhance …

Bone defect regeneration depends on the population and lifespan of M2 macrophages,
which are regulated by dual signals generated by the “physical” spatial configuration of …

The dysfunction of bone mesenchymal stem cells (BMSCs), caused by the physical and
chemical properties of the inflammatory and repair phases of bone regeneration, contributes …

Immunoregulation mediated bone tissue engineering (BTE) has demonstrated huge
potential in promoting repair of critical-size bone defects (CSBDs). The trade-off between …