Copper‐mediated nucleophilic radiofluorination of [18F]β‐CFT for positron emission tomography imaging of dopamine transporter
HM Yu, CY Li, SW Liu, CH Yang… - Journal of Labelled …, 2021 - Wiley Online Library
[18F] β‐CFT is a positron emission tomography (PET) ligand for imaging of dopamine
transporter. It was proved to be a sensitive PET marker to detect presynaptic dopaminergic …
transporter. It was proved to be a sensitive PET marker to detect presynaptic dopaminergic …
Preparation of [18F]β‐CFT‐FP and [11C]β‐CFT‐FP, selective radioligands for visualisation of the dopamine transporter using positron emission tomography (PET)
EL Kämäräinen, T Kyllönen… - Journal of Labelled …, 2000 - Wiley Online Library
In this study the N‐fluoropropyl analogue of the cocaine congener β‐CFT (I), N‐(3‐
fluoropropyl)‐2β‐carbomethoxy‐3β‐(4‐fluorophenyl) nortropane (β‐CFT‐FP, III), was …
fluoropropyl)‐2β‐carbomethoxy‐3β‐(4‐fluorophenyl) nortropane (β‐CFT‐FP, III), was …
An efficient synthesis of F18-FECNT, a PET tracer for dopamine transporter
D Murali, N Vandehey, B Christian, J Nickles, E Houser… - 2008 - Soc Nuclear Med
1229 Objectives: The aim of this work is to develop an efficient and cost effective method to
synthesize F18-FECNT, a PET tracer used for in vivo imaging of dopamine transporter …
synthesize F18-FECNT, a PET tracer used for in vivo imaging of dopamine transporter …
Simplified synthesis of N‐(3‐[18F]fluoropropyl)‐2β‐carbomethoxy‐3β‐(4‐fluorophenyl)nortropane ([18F]β‐CFT‐FP) using [18F]fluoropropyl tosylate as the …
T Koivula, O Perhola, EL Kämäräinen… - Journal of Labelled …, 2005 - Wiley Online Library
A synthesis method has been developed for the labelling of N‐(3‐[18F] fluoropropyl)‐2β‐
carbomethoxy‐3β‐(4‐fluorophenyl) nortropane ([18F] β‐CFT‐FP), a potential radioligand for …
carbomethoxy‐3β‐(4‐fluorophenyl) nortropane ([18F] β‐CFT‐FP), a potential radioligand for …
[PDF][PDF] Fluorine-18-FPCT: a PET radiotracer for imaging dopamine transporters
MM Goodman, R Keil, TM Shoup… - Journal of Nuclear …, 1997 - Soc Nuclear Med
Results: Tissue distributionstudies in rats with [18F] FPCTshowed high striatal uptake
(0.70% dose/g at 60 min; 0.38% dose/g at 120 min) and good striatal-to-cerebellum ratios …
(0.70% dose/g at 60 min; 0.38% dose/g at 120 min) and good striatal-to-cerebellum ratios …
An efficient one‐step radiosynthesis of [18F]FE‐PE2I, a PET radioligand for imaging of dopamine transporters
V Stepanov, R Krasikova, L Raus… - Journal of Labelled …, 2012 - Wiley Online Library
The aim of this study was to develop a direct fluorination method for the preparation of [18F]‐
(E)‐N‐(3‐iodoprop‐2‐enyl)‐2β‐carbofluoroethoxy‐3β‐(4′‐methyl‐phenyl) nortropane …
(E)‐N‐(3‐iodoprop‐2‐enyl)‐2β‐carbofluoroethoxy‐3β‐(4′‐methyl‐phenyl) nortropane …
One-step high-radiochemical-yield synthesis of [18F] FP-CIT using a protic solvent system
SJ Lee, SJ Oh, DY Chi, SH Kang, HS Kil, JS Kim… - Nuclear medicine and …, 2007 - Elsevier
Although [18F] fluoropropylcarbomethoxyiodophenylnortro… (FP-CIT) is a promising
radiopharmaceutical for dopamine transporter imaging, it has not been used for clinical …
radiopharmaceutical for dopamine transporter imaging, it has not been used for clinical …
Improved synthesis and metabolic stability analysis of the dopamine transporter ligand [18F] FECT
SK Chitneni, L Garreau, B Cleynhens, N Evens… - Nuclear medicine and …, 2008 - Elsevier
INTRODUCTION:[2′-[18F] Fluoroethyl (lR-2-exo-3-exe)-8-methyl-3-(4-chlorophenyl)-8-
azabicyclo [3.2. 1]-octane-2-carboxylate]([18F] FECT) is a positron emission tomography …
azabicyclo [3.2. 1]-octane-2-carboxylate]([18F] FECT) is a positron emission tomography …
Radiosynthesis of [18F]LBT‐999, a selective radioligand for the visualization of the dopamine transporter with PET
F Dollé, F Hinnen, P Emond, S Mavel… - Journal of Labelled …, 2006 - Wiley Online Library
Abstract LBT‐999 (8‐((E)‐4‐fluoro‐but‐2‐enyl)‐3β‐p‐tolyl‐8‐aza‐bicyclo [3.2. 1] octane‐2β‐
carboxylic acid methyl ester) is a cocaine derivative belonging to a new generation of highly …
carboxylic acid methyl ester) is a cocaine derivative belonging to a new generation of highly …
[HTML][HTML] Fully automated radiosynthesis of [18F]LBT999 on TRACERlab FXFN and AllinOne modules, a PET radiopharmaceutical for imaging the dopamine …
C Vala, C Mothes, G Chicheri, P Magadur… - EJNMMI …, 2020 - Springer
Abstract Background Fluorine labelled 8-((E)-4-fluoro-but-2-enyl)-3β-p-tolyl-8-aza-bicyclo
[3.2. 1] octane-2β-carboxylic acid methyl ester ([18 F] LBT999) is a selective radioligand for …
[3.2. 1] octane-2β-carboxylic acid methyl ester ([18 F] LBT999) is a selective radioligand for …
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