Introduction: Early assessment of a therapeutic response is a central goal in antidepressant
treatment. The present study examined the potential for therapeutic drug monitoring and …

Background: The therapeutic reference range for venlafaxine in antidepressant treatment
has been defined as 100 to 400 ng/mL. However, in an everyday setting active moiety …

Pattern analysis has been used to distinguish between the true effect of an antidepressant
and a placebo effect. The placebo effect constitutes clinical improvement that is attributable …

Objective Early clinical response to antidepressant treatment is an important therapeutic
goal, considering the psychological, social and economic consequences of depression. The …

Abstract Background Therapeutic Drug Monitoring (TDM) represents one of the most
promising tools in clinical practice to optimise antidepressant treatment. Nevertheless, little …

Venlafaxine, a new antidepressant, inhibits reuptake of norepinephrine and serotonin
without appreciable effects on histaminergic, alpha-adrenergic, or cholinergic systems …

Objective: Venlafaxine (VEN) is a widely used antidepressant drug, which is available in
both brand-name and generic formulations. Bioequivalence studies indicate some …

A large-scale, naturalistic trial was conducted in 1020 patients, 688 of whom switched to
venlafaxine from other antidepressant medications, primarily because of lack of efficacy with …

High doses of antidepressants are often used for treatment-resistant depression.
Venlafaxine, a dual serotonin and noradrenaline reuptake inhibitor, has been shown to have …

Study Objective. To compare treatment adequacy in the management of depression during
the acute and continuation phases between patients newly treated with venlafaxine …