Background: Malaria is on the increase due to emergence of parasite drug resistance and
there is thus an urgent need for the development of new antiparasitic drugs effective at low …

Azithromycin, an azalide analog of erythromycin was assayed for its in vitro activity against
multidrug-resistant Plasmodium falciparum K1 strain by measuring the 3H-hypoxanthine …

The antimalarial activity of combinations of mefloquine or artesunic acid with ciprofloxacin
and other synthetic fluoroquinolone was tested in vitro against Plasmodium falciparum using …

Introduction: The development of new antimalarial drugs is time-consuming and costly, thus
repurposing of drugs with initial indications for possible antimalarial indication is imperative …

During the last 2 decades there have been numerous reports of the emergence of
mefloquine resistance in Southeast Asia and nearly 50% resistance is reported in Thailand …

The combination effects of chloroquine with Cepharanthin" or minocycline hydrochloride
were evaluated against a blood-induced infection with chloroquine-resistant P. berghei NK …

SETTINGS: Experimental study. SUBJECTS AND METHODS: The parasiticidal profile was
studied in five chloroquine sensitive and five chloroquine resistant P. falciparum isolates …

Mefloquine base,(12.5 mg/kg body weight), was administered as a single oral dose to 34
pregnant women with Plasmodium falciparum parasitaemia. They were followed up in vivo …

Malaria remains one of the leading causes of disease and death in the tropics, mainly of
children under 5 years of age. Chloroquine began as a first-line antimalarial in 1946; it …

Isolates of P. falciparum were collected from 127 subjects recruited, for in-vivo trials of
mefloquine–artesunate, by the Cambodian Ministry of Health. All the subjects came from …