Illuminating the evolutionary history of chlamydiae

M Horn, A Collingro, S Schmitz-Esser, CL Beier… - Science, 2004 - science.org
Chlamydiae are the major cause of preventable blindness and sexually transmitted disease.
Genome analysis of a chlamydia-related symbiont of free-living amoebae revealed that it is …

Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis

RS Stephens, S Kalman, C Lammel, J Fan, R Marathe… - Science, 1998 - science.org
Analysis of the 1,042,519–base pair Chlamydia trachomatis genome revealed unexpected
features related to the complex biology of chlamydiae. Although chlamydiae lack many …

Pangenomics reveals alternative environmental lifestyles among chlamydiae

S Köstlbacher, A Collingro, T Halter, F Schulz… - Nature …, 2021 - nature.com
Chlamydiae are highly successful strictly intracellular bacteria associated with diverse
eukaryotic hosts. Here we analyzed metagenome-assembled genomes of the “Genomes …

Chlamydiae as Symbionts in Eukaryotes

M Horn - Annu. Rev. Microbiol., 2008 - annualreviews.org
Members of the phylum Chlamydiae are obligate intracellular bacteria that were discovered
about a century ago. Although Chlamydiae are major pathogens of humans and animals …

Closing in on Chlamydia and its intracellular bag of tricks

PM Bavoil, R Hsia, DM Ojcius - Microbiology, 2000 - microbiologyresearch.org
Background Various species of Chlamydia continue to provoke serious infections of humans
and animals worldwide, despite extensive work to better characterize the biology of the …

Genome sequencing and our understanding of chlamydiae

DD Rockey, J Lenart, RS Stephens - Infection and immunity, 2000 - Am Soc Microbiol
A driving force in the evolution of a microorganism is the ability to colonize a niche. A
vertebrate organism represents a unique niche, but to an infecting microbe it is simply an …

Chlamydiae as pathogens: new species and new issues.

RW Peeling, RC Brunham - Emerging infectious diseases, 1996 - ncbi.nlm.nih.gov
The recognition of genital chlamydial infection as an important public health problem was
made first by the recognition of its role in acute clinical syndromes, as well as in serious …

Chlamydial infection from outside to inside

A Gitsels, N Sanders, D Vanrompay - Frontiers in Microbiology, 2019 - frontiersin.org
Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic
developmental cycle. Specific interactions with the host cell are crucial for the bacteria's …

Evolution of Chlamydia trachomatis

IN Clarke - Annals of the New York Academy of Sciences, 2011 - Wiley Online Library
We know surprisingly little about the evolutionary origins of Chlamydia trachomatis. It causes
both ocular (trachoma) and sexually transmitted infections in humans, it is an obligate …

Chlamydia genomics: providing novel insights into chlamydial biology

NL Bachmann, A Polkinghorne, P Timms - Trends in microbiology, 2014 - cell.com
Chlamydiaceae are obligate intracellular pathogens that have successfully evolved to
colonize a diverse range of hosts. There are currently 11 described species of Chlamydia …