Nature employs a variety of tactics to precisely time and execute the processes and
mechanics of life, relying on sequential sense and response cascades to transduce …

Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive
devices that deliver a drug in spatial-, temporal-and dosage-controlled fashions have …

The application of organic polymers and inorganic/organic hybrid systems in numerous
fields of biotechnology has seen a considerable growth in recent years. Typically, organic …

Highlights•Nanomedicine is a promising strategy for target-specific delivery of
therapeutics.•Stimuli-responsive nanocarriers enhance tissue specificity.•Advances in …

Stimuli‐responsive materials are so named because they can alter their physicochemical
properties and/or structural conformations in response to specific stimuli. The stimuli can be …

Conspectus Cancer is a disease characterized by uncontrolled growth and division of
abnormal cells, which could be effectively suppressed by various therapeutic agents in …

Materials that respond to endogenous stimuli are being leveraged to enhance
spatiotemporal control in a range of biomedical applications from drug delivery to diagnostic …

To achieve the promise of stimuli-responsive drug delivery systems for the treatment of
cancer, they should (1) avoid premature clearance;(2) accumulate in tumors and undergo …

Nanotechnology has shown tremendous promise in target-specific delivery of drugs and
genes in the body. Although passive and active targeted-drug delivery has addressed a …

Our understanding of the biologic effects (including toxicity) of nanomaterials is incomplete.
In vivo animal studies remain the gold standard; however, widespread testing remains …