Lipophagy is the autophagic degradation of lipid droplets. Dysregulated lipophagy has been
implicated in the development of non-alcoholic fatty liver disease (NAFLD). Ajugol is an …

Background Lipophagy is an autophagic process, which delivers the intracellular lipid
droplets to the lysosomes for degradation. Recent studies revealed that the impairment of …

Formononetin has been reported to ameliorate hyperlipidemia and obesity, but its effect and
mechanism of action in anti-non-alcoholic fatty liver disease (NAFLD) remain unclear …

Non-alcoholic fatty liver disease (NAFLD) is the most common among lipid metabolism
disorders. Autophagy plays an important role in lipid metabolism in NAFLD. Pueraria …

Nonalcoholic fatty liver disease (NAFLD) results from an abnormal accumulation of lipids
within hepatocytes, and is commonly associated with obesity, insulin resistance, and …

Background Non-alcoholic fatty liver disease (NAFLD) is characterized by ectopic
accumulation of triglycerides in the liver. Emerging evidence has demonstrated that …

Nonalcoholic fatty liver disease (NAFLD) is considered to be a hepatic manifestation of the
metabolic syndrome, and the incidence of NAFLD is increasing rapidly. However …

Objective Abnormal autophagic function and activated inflammasomes are typical features
in the liver of patients with non-alcoholic steatohepatitis (NASH). Here, we explored whether …

Nonalcoholic steatohepatitis (NASH) is a progressive disorder with aberrant lipid
accumulation and subsequent inflammatory and profibrotic response. Therapeutic efforts at …

Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease worldwide. It
encompasses a spectrum ranging from simple steatosis to fatty liver with hepatocellular …