Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for
millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host …

Mycobacterium tuberculosis is a highly efficient pathogen, killing millions of infected people
annually. The capacity of M. tuberculosis to survive and cause disease is strongly correlated …

The ability of Mycobacterium tuberculosis to cause disease hinges upon successfully
thwarting the innate defenses of the macrophage host cell. The pathogen's trump card is its …

The intimate and persistent connection between Mycobacterium tuberculosis and its human
host suggests that the pathogen has evolved extensive mechanisms to evade eradication by …

The successful establishment and maintenance of a bacterial infection depend on the
pathogen's ability to subvert the host cell's defense response and successfully survive …

One-third of the global human population harbours Mycobacterium tuberculosis in dormant
form. This dormant or latent infection presents a major challenge for global efforts to …

Mycobacterium tuberculosis is an extremely successful pathogen that appears to have
coevolved with humans as its specific host species for thousands of years (1). This persistent …

Infection with Mycobacterium tuberculosis causes> 1.5 million deaths worldwide annually.
Innate immune cells are the first to encounter M. tuberculosis, and their response dictates …

Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), is an extremely
successful pathogen that adapts to survive within the host. During the latency phase of …

Mycobacterium tuberculosis is an extremely successful pathogen that demonstrates the
capacity to modulate its host both at the cellular and tissue levels. At the cellular level, the …