Integration of proteomic and metabolomic characterization in atrial fibrillation-induced heart failure
H Zhang, L Wang, D Yin, Q Zhou, L Lv, Z Dong, Y Shi - BMC genomics, 2022 - Springer
Background The exact mechanism of atrial fibrillation (AF)-induced heart failure (HF)
remains unclear. Proteomics and metabolomics were integrated to in this study, as to …
remains unclear. Proteomics and metabolomics were integrated to in this study, as to …
Comprehensive metabolomic and proteomic analyses reveal candidate biomarkers and related metabolic networks in atrial fibrillation
J Zhou, L Sun, L Chen, S Liu, L Zhong, M Cui - Metabolomics, 2019 - Springer
Introduction Atrial fibrillation (AF) is an abnormal heart rhythm characterized by an irregular
beating of the atria and is associated with an increased risk of heart failure, dementia, and …
beating of the atria and is associated with an increased risk of heart failure, dementia, and …
Metabolomic and proteomic analyses of persistent valvular atrial fibrillation and non-valvular atrial fibrillation
B Hu, W Ge, Y Wang, X Zhang, T Li, H Cui… - Frontiers in …, 2021 - frontiersin.org
Atrial fibrillation (AF) is an abnormal heart rhythm related to an increased risk of heart failure,
dementia, and stroke. The distinction between valvular and non-valvular AF remains a …
dementia, and stroke. The distinction between valvular and non-valvular AF remains a …
Proteomic profiles of patients with atrial fibrillation provide candidate biomarkers for diagnosis
WY Zhong, H Yang, YL Wang, Y Yang, CF Guo… - International Journal of …, 2021 - Elsevier
Background Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide with an
increasing risk of heart failure, stroke, and thromboembolic events. Currently distinct …
increasing risk of heart failure, stroke, and thromboembolic events. Currently distinct …
Using machine learning to identify proteomic and metabolomic signatures of stroke in atrial fibrillation
F Zhang, Y Zhang, Q Zhou, Y Shi, X Gao, S Zhai… - Computers in Biology …, 2024 - Elsevier
Atrial fibrillation (AF) is a common cardiac arrhythmia, with stroke being its most detrimental
comorbidity. The exact mechanism of AF related stroke (AFS) still needs to be explored. In …
comorbidity. The exact mechanism of AF related stroke (AFS) still needs to be explored. In …
Multiple targets related to mitochondrial function unveiled by metabolomics and proteomics profiles of hearts from atrial fibrillation patients
W Liu, B Hu, Y Wang, X Zhang, M Zhu, Y Shi… - Frontiers in …, 2023 - frontiersin.org
Background: The prominent mitochondrial metabolic changes of the atrium reportedly have
significant impact on electrical signals and structural remodeling which play important roles …
significant impact on electrical signals and structural remodeling which play important roles …
Comprehensive metabolomic characterization of atrial fibrillation
C Lu, C Liu, D Mei, M Yu, J Bai, X Bao… - Frontiers in …, 2022 - frontiersin.org
Background Using human humoral metabolomic profiling, we can discover the diagnostic
biomarkers and pathogenesis of disease. The specific characterization of atrial fibrillation …
biomarkers and pathogenesis of disease. The specific characterization of atrial fibrillation …
Pathophysiological pathways in patients with heart failure and atrial fibrillation
BT Santema, VA Arita, IE Sama… - Cardiovascular …, 2022 - academic.oup.com
Aims Atrial fibrillation (AF) and heart failure (HF) are two growing epidemics that frequently
co-exist. We aimed to gain insights into the underlying pathophysiological pathways in HF …
co-exist. We aimed to gain insights into the underlying pathophysiological pathways in HF …
Combined metabolic, phenomic and genomic data to prioritize atrial fibrillation-related metabolites
ZT Yan, JM Huang, WL Luo… - Experimental and …, 2019 - spandidos-publications.com
Metabolites in atrial fibrillation (AF) were characterized to further explore the molecular
mechanisms of AF by integrating metabolic, phenomic and genomic data. Gene expression …
mechanisms of AF by integrating metabolic, phenomic and genomic data. Gene expression …
[HTML][HTML] Biomarkers and key pathways in atrial fibrillation associated with mitral valve disease identified by multi-omics study
MY Li, HX Chen, HT Hou, J Wang, XC Liu… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background Mitral valve disease (MVD)-associated atrial fibrillation (AF) is one of the most
common arrhythmias with an increased risk of thromboembolic events. This study aimed to …
common arrhythmias with an increased risk of thromboembolic events. This study aimed to …
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