Foxp3-expressing regulatory T (T reg) cells have been implicated in parasite-driven
inhibition of host immunity during chronic infection. We addressed whether parasites can …

Helminth parasites defy immune exclusion through sophisticated evasion mechanisms,
including activation of host immunosuppressive regulatory T (Treg) cells. The mouse …

Helminth parasites infect an alarmingly large proportion of the world's population, primarily
within tropical regions, and their ability to down‐modulate host immunity is key to their …

Here, we show that Treg limit intestinal pathology during nematode infection and that they
control the onset and magnitude of the anti‐parasitic Th Th2 response. Using mice …

Helminth infection is frequently associated with the expansion of regulatory T cells (Tregs)
and suppression of immune responses to bystander antigens. We show that infection of …

The chronic nature of intestinal nematode infections suggests that these parasites have
evolved sophisticated immunomodulatory strategies. The induction of regulatory responses …

Helminthic infections protect mice from colitis in murine models of inflammatory bowel
disease and also may protect people. Helminths like Heligmosomoides polygyrus bakeri …

Parasitic nematodes typically modulate T-cell reactivity, primarily during the chronic phase of
infection. We analyzed the role of CD4-positive (CD4+) T effector (Teff) cells and regulatory …

To escape expulsion by their host's immune system, pathogenic nematodes exploit
regulatory pathways that are intrinsic parts of the mammalian immune system, such as …

Although several markers have been associated with the characterization of regulatory T
cells (Tregs) and their function, no studies have investigated the dynamics of their …