Treatment effects of interleukin-6 receptor antibodies for modulating the systemic inflammatory response after out-of-hospital cardiac arrest (The IMICA Trial) a double …
MAS Meyer, S Wiberg, J Grand, ASP Meyer… - Circulation, 2021 - Am Heart Assoc
Background: Patients experiencing out-of-hospital cardiac arrest who remain comatose after
initial resuscitation are at high risk of morbidity and mortality attributable to the ensuing post …
initial resuscitation are at high risk of morbidity and mortality attributable to the ensuing post …
Inflammatory markers following resuscitation from out-of-hospital cardiac arrest—a prospective multicenter observational study
MA Peberdy, LW Andersen, A Abbate, LR Thacker… - Resuscitation, 2016 - Elsevier
Aim The post-cardiac arrest syndrome is a complex set of pathophysiological processes
including a systemic inflammatory response. The goal of the current investigation was to test …
including a systemic inflammatory response. The goal of the current investigation was to test …
Randomized trial of interleukin-6 receptor inhibition in patients with acute ST-segment elevation myocardial infarction
K Broch, AK Anstensrud, S Woxholt, K Sharma… - Journal of the American …, 2021 - jacc.org
Background Prompt myocardial revascularization with percutaneous coronary intervention
(PCI) reduces infarct size and improves outcomes in patients with ST-segment elevation …
(PCI) reduces infarct size and improves outcomes in patients with ST-segment elevation …
Successful cardiopulmonary resuscitation after cardiac arrest as a “sepsis-like” syndrome
C Adrie, M Adib-Conquy, I Laurent, M Monchi… - Circulation, 2002 - Am Heart Assoc
Background—We investigated the immunoinflammatory profile of patients successfully
resuscitated after cardiac arrest, representing a model of whole-body ischemia/reperfusion …
resuscitated after cardiac arrest, representing a model of whole-body ischemia/reperfusion …
Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction
O Kleveland, T Ueland, G Kunszt, M Bratlie… - International Journal of …, 2018 - Elsevier
Aim To evaluate the effect of interleukin-6 inhibition with tocilizumab on the cytokine network
in patients with acute non-ST-elevation myocardial infarction (NSTEMI). Methods 117 …
in patients with acute non-ST-elevation myocardial infarction (NSTEMI). Methods 117 …
[HTML][HTML] The inflammatory response is related to circulatory failure after out-of-hospital cardiac arrest: A prospective cohort study
H Langeland, JK Damås, TE Mollnes, JK Ludviksen… - Resuscitation, 2022 - Elsevier
Background Whole body ischemia and reperfusion injury after cardiac arrest leads to the
massive inflammation clinically manifested in the post-cardiac arrest syndrome. Previous …
massive inflammation clinically manifested in the post-cardiac arrest syndrome. Previous …
The role of inflammatory cytokines in cardiac arrest
C Jou, R Shah, A Figueroa… - Journal of intensive care …, 2020 - journals.sagepub.com
Introduction: Post-cardiac arrest syndrome (PCAS) is characterized by systemic
ischemia/reperfusion injury, anoxic brain injury, and post-arrest myocardial dysfunction …
ischemia/reperfusion injury, anoxic brain injury, and post-arrest myocardial dysfunction …
Predictive value of interleukin-6 in post-cardiac arrest patients treated with targeted temperature management at 33 C or 36 C
Aim Post-cardiac arrest syndrome (PCAS) is characterized by systemic inflammation,
however data on the prognostic value of inflammatory markers is sparse. We sought to …
however data on the prognostic value of inflammatory markers is sparse. We sought to …
Level of systemic inflammation and endothelial injury is associated with cardiovascular dysfunction and vasopressor support in post-cardiac arrest patients
J Bro-Jeppesen, PI Johansson, J Kjaergaard… - Resuscitation, 2017 - Elsevier
Aim Post-cardiac arrest syndrome (PCAS) is characterized by a sepsis-like inflammatory
response and hemodynamic instability. We investigated the associations between systemic …
response and hemodynamic instability. We investigated the associations between systemic …
The immunology of the post-cardiac arrest syndrome
CA Cunningham, PJ Coppler, AB Skolnik - Resuscitation, 2022 - Elsevier
Patients successfully resuscitated from cardiac arrest often have brain injury, myocardial
dysfunction, and systemic ischemia–reperfusion injury, collectively termed the post-cardiac …
dysfunction, and systemic ischemia–reperfusion injury, collectively termed the post-cardiac …
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