Human metabolites of cannabidiol: a review on their formation, biological activity, and relevance in therapy

I Ujváry, L Hanuš - Cannabis and cannabinoid research, 2016 - liebertpub.com
Cannabidiol (CBD), the main nonpsychoactive constituent of Cannabis sativa, has shown a
wide range of therapeutically promising pharmacological effects either as a sole drug or in …

Cannabidiol–recent advances

R Mechoulam, M Peters… - Chemistry & …, 2007 - Wiley Online Library
The aim of this review is to present some of the recent publications on cannabidiol (CBD; 2),
a major non‐psychoactive constituent of Cannabis, and to give a general overview. Special …

Cannabidiol: pharmacology and therapeutic targets

SC Britch, S Babalonis, SL Walsh - Psychopharmacology, 2021 - Springer
Rationale Cannabidiol (CBD) products lacking regulatory approval are being used to self-
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …

Current status and prospects for cannabidiol preparations as new therapeutic agents

PS Fasinu, S Phillips, MA ElSohly… - … : The Journal of Human …, 2016 - Wiley Online Library
States and the federal government are under growing pressure to legalize the use of
cannabis products for medical purposes in the United States. Sixteen states have legalized …

Molecular and cellular mechanisms of action of cannabidiol

N Martinez Naya, J Kelly, G Corna, M Golino, A Abbate… - Molecules, 2023 - mdpi.com
Cannabidiol (CBD) is the primary non-psychoactive chemical from Cannabis Sativa, a plant
used for centuries for both recreational and medicinal purposes. CBD lacks the psychotropic …

The essential medicinal chemistry of cannabidiol (CBD)

KM Nelson, J Bisson, G Singh, JG Graham… - Journal of medicinal …, 2020 - ACS Publications
This Perspective of the published essential medicinal chemistry of cannabidiol (CBD)
provides evidence that the popularization of CBD-fortified or CBD-labeled health products …

[HTML][HTML] Cannabidiol in humans—the quest for therapeutic targets

S Zhornitsky, S Potvin - Pharmaceuticals, 2012 - mdpi.com
Cannabidiol (CBD), a major phytocannabinoid constituent of cannabis, is attracting growing
attention in medicine for its anxiolytic, antipsychotic, antiemetic and anti-inflammatory …

[HTML][HTML] Therapeutic efficacy of cannabidiol (CBD): a review of the evidence from clinical trials and human laboratory studies

DJ Sholler, L Schoene, TR Spindle - Current addiction reports, 2020 - Springer
Rigorous, controlled evidence for the therapeutic efficacy of CBD is lacking for many health
conditions. Possible concerns with the use of CBD as a therapeutic include the potential for …

[HTML][HTML] A systematic review on the pharmacokinetics of cannabidiol in humans

SA Millar, NL Stone, AS Yates… - Frontiers in …, 2018 - frontiersin.org
Background: Cannabidiol is being pursued as a therapeutic treatment for multiple
conditions, usually by oral delivery. Animal studies suggest oral bioavailability is low, but …

Pharmacokinetic investigation of synthetic cannabidiol oral formulations in healthy volunteers

D Izgelov, E Davidson, D Barasch, A Regev… - European Journal of …, 2020 - Elsevier
Recent advances in the research of medicinal cannabis has placed the non-intoxicating
cannabinoid cannabidiol (CBD) at the front of scientific research. The reasons behind this …