Cadmium contributes to cardiac metabolic disruption by activating endothelial HIF1A-GLUT1 axis

X Zhang, W Zheng, S Sun, Y Du, W Xu, Z Sun, F Liu… - Cellular …, 2024 - Elsevier
Cadmium (Cd) is an environmental risk factor of cardiovascular diseases. Researchers have
found that Cd exposure causes energy metabolic disorders in the heart decades ago …

Cadmium exposure induces cardiac glucometabolic dysregulation and lipid accumulation independent of pyruvate dehydrogenase activity

OI Oluranti, EA Agboola, NE Fubara, MO Ajayi… - Annals of …, 2021 - Taylor & Francis
Context Suppressed glucose metabolism, elevated fatty acid metabolism and lipid
deposition within myocardial cells are the key pathological features of diabetic …

[HTML][HTML] Cadmium exposure disturbs myocardial lipid signature and induces inflammation in C57BL/6J mice

X Lin, Y Xu, T Tong, J Zhang, H He, L Yang… - Ecotoxicology and …, 2023 - Elsevier
Cadmium is a highly ubiquitous environmental pollutant that poses a serious threat to
human health. In this study, we assessed the cardiotoxicity of Cd exposure and explored the …

Chronic Cadmium Exposure Aggravates the Cardiac Dysfunction in Type 2 Diabetic Mice by Promoting Inflammation and Fibrosis

X Liu, S Wang, M Li, J Li, Z Sheng - 2021 - researchsquare.com
Background: Diabetic cardiomyopathy (DCM) is a serious diabetic complication with high
mortality. Cadmium (Cd) is a ubiquitous environmental contaminant and plays an important …

Cadmium exposure induces a sex-dependent decline in left ventricular cardiac function

ML Fitch, R Kabir, OV Ebenebe, N Taube, H Garbus… - Life sciences, 2023 - Elsevier
Aims Cadmium exposure is a worldwide problem that has been linked to the development of
cardiovascular disease. This study aimed to elucidate mechanistic details of chronic …

Cadmium Exposure and Cardiovascular Diseases

P Rasin, A Sreekanth - Chemical Research in Toxicology, 2023 - ACS Publications
Cadmium Exposure and Cardiovascular Diseases | Chemical Research in Toxicology ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Research in Toxicology ACS …

Cadmium exposure decreases fasting blood glucose levels and exacerbates type-2 diabetes in a mouse model

M Li, S Wang, X Liu, Z Sheng, B Li, J Li, J Zhang… - Endocrine, 2022 - Springer
Purpose Although the effects of cadmium (Cd) on the development of diabetes have been
extensively investigated, the relationship between Cd exposure and the severity of …

Subchronic cadmium exposure upregulates the mRNA level of genes associated to hepatic lipid metabolism in adult female CD1 mice

J Zhang, Y Wang, L Fu, YJ Feng, YL Ji… - Journal of Applied …, 2018 - Wiley Online Library
Cadmium (Cd) is a persistent environmental and occupational contaminant that
accumulates in humans and shows adverse effects on health. Accumulating evidence …

Cadmium exposure induces endothelial dysfunction via disturbing lipid metabolism in human microvascular endothelial cells

H Liang, R Yue, C Zhou, M Liu, X Yu… - Journal of Applied …, 2021 - Wiley Online Library
Cadmium (Cd) is an occupational and environmental heavy metal pollutant derived from
many sources that is linked to endothelial homeostasis. The endothelium is an important site …

Short-term Effects of Cadmium Exposure on Blood Pressure and Vascular Function in Wistar Rats

KA Rossi, CCP Almenara, RP Simões… - … Trace Element Research, 2024 - Springer
Chronic cadmium exposure is known to be associated with vascular changes and increased
blood pressure, but its short-term effects on the cardiovascular system remain poorly …