[HTML][HTML] Mechanisms of fluoride toxicity: from enzymes to underlying integrative networks

A Strunecka, O Strunecky - Applied Sciences, 2020 - mdpi.com
Fluoride has been employed in laboratory investigations since the early 20th century. These
studies opened the understanding of fluoride interventions to fundamental biological …

Molecular mechanisms of fluoride toxicity

O Barbier, L Arreola-Mendoza, LM Del Razo - Chemico-biological …, 2010 - Elsevier
Halfway through the twentieth century, fluoride piqued the interest of toxicologists due to its
deleterious effects at high concentrations in human populations suffering from fluorosis and …

Challenges of fluoride pollution in environment: mechanisms and pathological significance of toxicity–a review

S Wu, Y Wang, M Iqbal, K Mehmood, Y Li, Z Tang… - Environmental …, 2022 - Elsevier
Fluoride is an important trace element in the living body. A suitable amount of fluoride has a
beneficial effect on the body, but disproportionate fluoride entering the body will affect …

Recent advances in cellular effects of fluoride: an update on its signalling pathway and targeted therapeutic approaches

AH Nagendra, B Bose, S Shenoy P - Molecular Biology Reports, 2021 - Springer
Fluoride is a natural element essential in minute quantities in human's to maintain dental
and skeletal health. However, the disease fluorosis manifests itself due to excessive fluoride …

Principles of fluoride toxicity and the cellular response: a review

NR Johnston, SA Strobel - Archives of toxicology, 2020 - Springer
Fluoride is ubiquitously present throughout the world. It is released from minerals, magmatic
gas, and industrial processing, and travels in the atmosphere and water. Exposure to low …

Fluoride interactions: from molecules to disease

A Strunecka, J Patocka, RL Blaylock… - Current Signal …, 2007 - ingentaconnect.com
Fluoride has long been known to influence the activity of various enzymes in vitro. Later it
has been demonstrated that many effects primarily attributed to fluoride are caused by …

Toxic effects of fluoride on organisms

H Zuo, L Chen, M Kong, L Qiu, P Lü, P Wu, Y Yang… - Life sciences, 2018 - Elsevier
Accumulation of excess fluoride in the environment poses serious health risks to plants,
animals, and humans. This endangers human health, affects organism growth and …

Fluoride induced neurobehavioral impairments in experimental animals: a brief review

H Ottappilakkil, S Babu, S Balasubramanian… - … Trace Element Research, 2023 - Springer
Fluoride is one of the major toxicants in the environment and is often found in drinking water
at higher concentrations. Living organisms including humans exposed to high fluoride levels …

Fluoride and human health: Systematic appraisal of sources, exposures, metabolism, and toxicity

H Kabir, AK Gupta, S Tripathy - Critical Reviews in Environmental …, 2020 - Taylor & Francis
Fluoride (F−) originating from many natural geologic sources and anthropogenic activities
has imposed a substantial environmental health risk. More than 200 million people from …

The pathogenesis of endemic fluorosis: Research progress in the last 5 years

W Wei, S Pang, D Sun - Journal of cellular and molecular …, 2019 - Wiley Online Library
Fluorine is one of the trace elements necessary for health. It has many physiological
functions, and participates in normal metabolism. However, fluorine has paradoxical effects …