Women born to mothers who smoked during pregnancy have been shown to have imparied
fertility, although the mechanisms underlying this association are unknown. Nicotine …

PMSG-primed and hCG-triggered rat ovaries were exposed to nicotine and its major
metabolite, cotinine, using in vitro and in vivo experimental approaches. In vivo, a dose …

The objective of this study was to determine the effect of in utero and lactational exposure to
nicotine on the male reproductive tract. Dams were randomly assigned to receive saline or …

We have previously shown that in utero nicotine exposure causes impaired fertility, follicle
immaturity, and ovarian dysfunction in adult female rat offspring. These characteristics …

In order to study the effects of nicotine on pregnancy and fetal development, rats were
injected twice daily throughout gestation with graded doses of nicotine (1, 3, and 5 mg/kg) …

REPRODUCTION Page 1 REPRODUCTION RESEARCH Prenatal and lactation nicotine
exposure affects Sertoli cell and gonadotropin levels in rats CC Paccola and SM Miraglia …

In the present paper, we found that human fetal ovaries (at~ 16 weeks) express the
transcripts for several subunits of the nicotinic acetylcholine receptor (nAChR). Exposure to …

The effect of nicotine on the meiotic maturation of cultured hamster oocytes was
investigated. Oocytes were cultured for up to 24 h and meiotic status was scored …

A finite number of oocytes are established within the mammalian ovary prior to birth to form a
precious ovarian reserve. Damage to this limited pool of gametes by environmental factors …

The theory of fetal origins of adult disease was first proposed in 1989, and in the decades
since, a wide range of other diseases from obesity to asthma have been found to originate in …