[Frontiers in Bioscience 6, e77-92, October 1, 2001] 77 ROLE OF MÜLLER CELLS IN RETINAL
DEGENERATIONS Andreas Bringmann and And Page 1 [Frontiers in Bioscience 6, e77-92 …

Müller glial cells span the entire thickness of the tissue, and ensheath all retinal neurons, in
vertebrate retinae of all species. This morphological relationship is reflected by a multitude …

Müller glial cells ensheath all retinal neurons in vertebrate retinae. There are a multitude of
functional interactions between neurons and Müller cells, including delivery of the light …

Highlights•This review reflects on the dual response of Müller cell after injury.•We review the
features that position Müller cells as a promising therapeutic target.•We discuss methods for …

Müller cells are active players in normal retinal function and in virtually all forms of retinal
injury and disease. Reactive Müller cells protect the tissue from further damage and …

Müller cells are one of the primary glial cell types found in the retina and play a significant
role in maintaining retinal function and health. Since Müller cells are the only cell type to …

Müller cells, the major type of glial cells in the retina, are responsible for the homeostatic and
metabolic support of retinal neurons. By mediating transcellular ion, water, and bicarbonate …

Virtually all pathogenic stimuli activate Müller cells. Reactive Müller cells exert protective
and toxic effects on photoreceptors and neurons. They contribute to oxidative stress and …

Background Proliferative retinopathies are considered to represent maladapted retinal
wound repair processes driven by growth factor-and cytokine-induced overstimulation of …

Despite advances in surgical management of fibrocontractive retinal disorders, proliferative
vitreoretinopathy (PVR) and proliferative diabetic retinopathy (PDR) remain major causes of …