[HTML][HTML] Highlights on distinctive structural and functional properties of HTLV Tax proteins
MG Romanelli, E Diani, E Bergamo, C Casoli… - Frontiers in …, 2013 - frontiersin.org
Human T cell leukemia viruses (HTLVs) are complex human retroviruses of the
Deltaretrovirus genus. Four types have been identified thus far, with HTLV-1 and HTLV-2 …
Deltaretrovirus genus. Four types have been identified thus far, with HTLV-1 and HTLV-2 …
[HTML][HTML] Tax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation
Although human T cell leukemia virus type 1 and 2 (HTLV-1 and HTLV-2) share similar
genetic organization, they have major differences in their pathogenesis and disease …
genetic organization, they have major differences in their pathogenesis and disease …
[HTML][HTML] Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway
A Lavorgna, EW Harhaj - Viruses, 2014 - mdpi.com
Human T-cell leukemia virus type 1 (HTLV-1) is a complex retrovirus that infects CD4+ T
cells and causes adult T-cell leukemia/lymphoma (ATLL) in 3%–5% of infected individuals …
cells and causes adult T-cell leukemia/lymphoma (ATLL) in 3%–5% of infected individuals …
Human T-cell leukemia virus type 2 tax mutants that selectively abrogate NFκB or CREB/ATF activation fail to transform primary human T cells
TM Ross, M Narayan, ZY Fang, AC Minella… - Journal of …, 2000 - Am Soc Microbiol
Human T-cell leukemia virus (HTLV) Tax protein has been implicated in the HTLV
oncogenic process, primarily due to its pleiotropic effects on cellular genes involved in …
oncogenic process, primarily due to its pleiotropic effects on cellular genes involved in …
Human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 tax oncoproteins modulate cell cycle progression and apoptosis
M Sieburg, A Tripp, JW Ma, G Feuer - Journal of virology, 2004 - Am Soc Microbiol
Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia
and lymphoma, an aggressive clonal malignancy of human CD4-bearing T lymphocytes …
and lymphoma, an aggressive clonal malignancy of human CD4-bearing T lymphocytes …
The HTLV-1 Tax protein inhibits formation of stress granules by interacting with histone deacetylase 6
S Legros, M Boxus, JS Gatot, C Van Lint, V Kruys… - Oncogene, 2011 - nature.com
Human T cell leukemia virus type-1 (HTLV-1) is the causative agent of two major diseases: a
rapidly fatal leukemia designated adult T-cell leukemia and a neurological degenerative …
rapidly fatal leukemia designated adult T-cell leukemia and a neurological degenerative …
Molecular mechanisms of cellular transformation by HTLV-1 Tax
R Grassmann, M Aboud, KT Jeang - Oncogene, 2005 - nature.com
The HTLV Tax protein is crucial for viral replication and for initiating malignant
transformation leading to the development of adult T-cell leukemia. Tax has been shown to …
transformation leading to the development of adult T-cell leukemia. Tax has been shown to …
Intracellular localization and cellular factors interaction of HTLV-1 and HTLV-2 Tax proteins: similarities and functional differences
U Bertazzoni, M Turci, F Avesani, G Di Gennaro… - Viruses, 2011 - mdpi.com
Human T-lymphotropic viruses type 1 (HTLV-1) and type 2 (HTLV-2) present very similar
genomic structures but HTLV-1 is more pathogenic than HTLV-2. Is this difference due to …
genomic structures but HTLV-1 is more pathogenic than HTLV-2. Is this difference due to …
Genome-wide expression changes induced by HTLV-1 Tax: evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-κB activation
PWP Ng, H Iha, Y Iwanaga, M Bittner, Y Chen, Y Jiang… - Oncogene, 2001 - nature.com
The Tax protein of human T-lymphotropic virus type 1 (HTLV-1), an oncoprotein that
transactivates viral and cellular genes, plays a key role in HTLV-1 replication and …
transactivates viral and cellular genes, plays a key role in HTLV-1 replication and …
[HTML][HTML] Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2
T Shoji, M Higuchi, R Kondo, M Takahashi, M Oie… - Retrovirology, 2009 - Springer
Background Human T-cell leukemia virus type 1 (HTLV-1) is a causative agent of adult T-cell
leukemia (ATL), whereas its relative HTLV-2 is not associated with any malignancies …
leukemia (ATL), whereas its relative HTLV-2 is not associated with any malignancies …