Stable ubiquitination of human T-cell leukemia virus type 1 tax is required for proteasome binding

E Chiari, I Lamsoul, J Lodewick, C Chopin… - Journal of …, 2004 - Am Soc Microbiol
Human T-cell leukemia virus type 1 (HTLV-1) is the retrovirus responsible for adult T-cell
leukemia and HTLV-1-associated myelopathy. Adult T-cell leukemia development is mainly …

Mechanisms of Tax regulation of human T cell leukemia virus type I gene expression

AA Franklin, JK Nyborg - Journal of Biomedical Science, 1995 - karger.com
During the last several years, the human T cell leukemia virus type I (HTLY-I) has become
recognized as an important cause for public health concern throughout the world. HTLY-I is …

HTLV-1 bZIP factor protein targets the Rb/E2F-1 pathway to promote proliferation and apoptosis of primary CD4+ T cells

A Kawatsuki, JI Yasunaga, Y Mitobe, PL Green… - Oncogene, 2016 - nature.com
Human T-cell leukemia virus type 1 (HTLV-1) is the etiological agent of a malignancy of
CD4+CD25+ T cells, adult T-cell leukemia (ATL) and several inflammatory diseases such as …

Human T-cell lymphotropic virus type 3: complete nucleotide sequence and characterization of the human tax3 protein

S Calattini, SA Chevalier, R Duprez, P Afonso… - Journal of …, 2006 - Am Soc Microbiol
We and others have recently uncovered the existence of human T-cell lymphotropic virus
type 3 (HTLV-3), the third member of the HTLV family. We have now sequenced the full …

Multiple viral strategies of HTLV-1 for dysregulation of cell growth control

M Yoshida - Annual review of immunology, 2001 - annualreviews.org
The human T cell leukemia virus-1 (HTLV-1) is a retrovirus that causes adult T cell leukemia
(ATL) and neurological disorder, the tropical spastic paraparesis (HAM/TSP). The …

PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell line

C Tsubata, M Higuchi, M Takahashi, M Oie, Y Tanaka… - Retrovirology, 2005 - Springer
Background Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-
cell leukemia (ATL), whereas HTLV type 2 (HTLV-2), is not associated with ATL or any other …

Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity

I Azran, Y Schavinsky-Khrapunsky, M Aboud - Retrovirology, 2004 - Springer
HTLV-1 is the etiological agent of adult T-cell leukemia (ATL), the neurological syndrome
TSP/HAM and certain other clinical disorders. The viral Tax protein is considered to play a …

Human T-cell leukemia virus type 2 (HTLV-2) Tax protein transforms a rat fibroblast cell line but less efficiently than HTLV-1 Tax

K Endo, A Hirata, K Iwai, M Sakurai, M Fukushi… - Journal of …, 2002 - Am Soc Microbiol
Human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 are retroviruses with similar
biological properties. Whereas HTLV-1 is the causative agent of an aggressive T-cell …

New insight into the oncogenic mechanism of the retroviral oncoprotein Tax

H Cheng, T Ren, S Sun - Protein & cell, 2012 - Springer
HTLV-1 viral genome encodes three main structural gene products including Gag, reverse
transcriptase (Pol/RT) and envelope protein (Env), and it also expresses several viral …

[PDF][PDF] Molecular interactions between HTLV-1 Tax protein and the NF-κB/IκB transcription complex

J Hiscott, L PETROPOULOS, J LACOSTE - Virology, 1995 - core.ac.uk
The human T cell lymphotropic virus (HTLV-1) is the 2, IL-2R-a, GM-CSF, c-fos, vimentin, IL-
6 (reviewed in Yoshida, 1993). Since Tax is not a DNA binding protein etiologic agent of …