[HTML][HTML] Phase I/II open-label trial of intravenous allogeneic mesenchymal stromal cell therapy in adults with recessive dystrophic epidermolysis bullosa
Background Recessive dystrophic epidermolysis bullosa (RDEB) is a hereditary blistering
disorder due to a lack of type VII collagen. At present, treatment is mainly supportive …
disorder due to a lack of type VII collagen. At present, treatment is mainly supportive …
[HTML][HTML] Potential of systemic allogeneic mesenchymal stromal cell therapy for children with recessive dystrophic epidermolysis bullosa
G Petrof, SM Lwin, M Martinez-Queipo… - The Journal of …, 2015 - ncbi.nlm.nih.gov
The skin fragility disorder recessive dystrophic epidermolysis bullosa (RDEB) results from
mutations in COL7A1 leading to reduced or absent type VII collagen (C7) and defective …
mutations in COL7A1 leading to reduced or absent type VII collagen (C7) and defective …
A phase II randomized vehicle-controlled trial of intradermal allogeneic fibroblasts for recessive dystrophic epidermolysis bullosa
SS Venugopal, W Yan, JW Frew, HI Cohn… - Journal of the American …, 2013 - Elsevier
Background Chronic wounds are a major source of morbidity and mortality in generalized
severe recessive dystrophic epidermolysis bullosa (RDEB-GS). Objective This was a phase …
severe recessive dystrophic epidermolysis bullosa (RDEB-GS). Objective This was a phase …
Bone marrow stem cell therapy for recessive dystrophic epidermolysis bullosa
M Kiuru, M Itoh, MS Cairo, AM Christiano - Dermatologic clinics, 2010 - derm.theclinics.com
The dystrophic forms of epidermolysis bullosa are a group of inherited blistering disorders
caused by mutations in the type VII collagen gene (COL7A1). 1 Recessive dystrophic …
caused by mutations in the type VII collagen gene (COL7A1). 1 Recessive dystrophic …
[HTML][HTML] Intravenous allogeneic umbilical cord blood–derived mesenchymal stem cell therapy in recessive dystrophic epidermolysis bullosa patients
SE Lee, SJ Lee, SE Kim, K Kim, B Cho, K Roh, SC Kim - JCI insight, 2021 - ncbi.nlm.nih.gov
BACKGROUND Recessive dystrophic epidermolysis bullosa (RDEB) is an incurable
disease that causes severe mucocutaneous fragility due to mutations in COL7A1 (encoding …
disease that causes severe mucocutaneous fragility due to mutations in COL7A1 (encoding …
Treatment of dystrophic epidermolysis bullosa with bone marrow non‐hematopoeitic stem cells: a randomized controlled trial
M El‐Darouti, M Fawzy, I Amin… - Dermatologic …, 2016 - Wiley Online Library
Patients with dystrophic epidermolysis bullosa (DEB) have mutations in type VII collagen
gene. Type VII collagen is synthesized by keratinocytes and fibroblasts. Based on the ability …
gene. Type VII collagen is synthesized by keratinocytes and fibroblasts. Based on the ability …
[HTML][HTML] Long-term safety and efficacy of gene-corrected autologous keratinocyte grafts for recessive dystrophic epidermolysis bullosa
JY So, J Nazaroff, CV Iwummadu, N Harris… - Orphanet Journal of …, 2022 - Springer
Background Recessive dystrophic epidermolysis bullosa (RDEB) is a rare, devastating
blistering genodermatosis caused by mutations in the COL7A1 gene, which encodes for …
blistering genodermatosis caused by mutations in the COL7A1 gene, which encodes for …
[HTML][HTML] Preconditioning of mesenchymal stem cells for improved transplantation efficacy in recessive dystrophic epidermolysis bullosa
C Perdoni, JA McGrath, J Tolar - Stem cell research & therapy, 2014 - Springer
Introduction The use of hematopoietic cell transplantation (HCT) has previously been shown
to ameliorate cutaneous blistering in pediatric patients with recessive dystrophic …
to ameliorate cutaneous blistering in pediatric patients with recessive dystrophic …
[PDF][PDF] Fibroblast-based cell therapy strategy for recessive dystrophic epidermolysis bullosa
WF Yan, DF Murrell - Dermatologic clinics, 2010 - Citeseer
Dystrophic epidermolysis bullosa (DEB) is a severe skin fragility disorder associated with
trauma-induced blistering, progressive soft tissue scarring, and increased risk of skin cancer …
trauma-induced blistering, progressive soft tissue scarring, and increased risk of skin cancer …
Systemic granulocyte colony-stimulating factor (G-CSF) enhances wound healing in dystrophic epidermolysis bullosa (DEB): Results of a pilot trial
JD Fine, B Manes, H Frangoul - Journal of the American Academy of …, 2015 - Elsevier
Background Chronic nonhealing wounds are the norm in patients with inherited
epidermolysis bullosa (EB), especially those with dystrophic EB (DEB). A possible benefit in …
epidermolysis bullosa (EB), especially those with dystrophic EB (DEB). A possible benefit in …