Circulating microRNAs as biomarkers for disease staging in multiple sclerosis
Objective MicroRNAs (miRNAs) are single‐stranded, small noncoding RNAs that regulate
gene expression. Because they are stable in serum, they are being developed as …
gene expression. Because they are stable in serum, they are being developed as …
Regulated microRNAs in the CSF of patients with multiple sclerosis: a case-control study
A Haghikia, A Haghikia, K Hellwig, A Baraniskin… - Neurology, 2012 - AAN Enterprises
Objective: MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression
and serve as promising therapeutic targets in many diseases. MiRNAs are also present in …
and serve as promising therapeutic targets in many diseases. MiRNAs are also present in …
Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis
Objective: To identify circulating microRNAs (miRNAs) linked to disease stage and disability
in multiple sclerosis (MS). Methods: Sera from 296 participants including patients with MS …
in multiple sclerosis (MS). Methods: Sera from 296 participants including patients with MS …
Circulating microRNAs as biomarkers in progressive multiple sclerosis
J Vistbakka, I Elovaara, T Lehtimäki… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Background: In multiple sclerosis (MS), microRNA (miRNA) dysregulation is mostly reported
in different immune cells, but less information is available on circulating miRNAs that exert …
in different immune cells, but less information is available on circulating miRNAs that exert …
Identification of MS-specific serum miRNAs in an international multicenter study
Objective To identify circulating microRNAs (miRNAs) linked to disease, disease stage, and
disability in MS across cohorts. Methods Samples were obtained from the Comprehensive …
disability in MS across cohorts. Methods Samples were obtained from the Comprehensive …
Association between serum MicroRNAs and magnetic resonance imaging measures of multiple sclerosis severity
Importance MicroRNAs (miRNAs) are promising multiple sclerosis (MS) biomarkers.
Establishing the association between miRNAs and magnetic resonance imaging (MRI) …
Establishing the association between miRNAs and magnetic resonance imaging (MRI) …
Comprehensive analysis of microRNA profiles in multiple sclerosis including next-generation sequencing
A Keller, P Leidinger, F Steinmeyer… - Multiple Sclerosis …, 2014 - journals.sagepub.com
Background: MicroRNAs (miRNAs) are short, noncoding RNAs with gene regulatory
functions whose expression profiles may serve as disease biomarkers. Objective: The …
functions whose expression profiles may serve as disease biomarkers. Objective: The …
[HTML][HTML] Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls
A Keller, P Leidinger, J Lange, A Borries, H Schroers… - PloS one, 2009 - journals.plos.org
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system, which is heterogenous with respect to clinical manifestations and response …
nervous system, which is heterogenous with respect to clinical manifestations and response …
Differential microRNA expression in blood in multiple sclerosis
HB Søndergaard, D Hesse, M Krakauer… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: microRNAs (miRNAs) regulate the expression of the genome at the post-
transcriptional level. They play a role in autoimmunity and inflammation, and show potential …
transcriptional level. They play a role in autoimmunity and inflammation, and show potential …
Decreased circulating miRNA levels in patients with primary progressive multiple sclerosis
C Fenoglio, E Ridolfi, C Cantoni… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Emerging evidence underlines the importance of micro (mi) RNAs in the pathogenesis of
multiple sclerosis (MS). Free-circulating miRNAs were investigated in serum from MS …
multiple sclerosis (MS). Free-circulating miRNAs were investigated in serum from MS …