Second-trimester ultrasound to detect fetuses with Down syndrome: a meta-analysis
R Smith-Bindman, W Hosmer, VA Feldstein, JJ Deeks… - Jama, 2001 - jamanetwork.com
ContextSecond-trimester prenatal ultrasound is widely used in an attempt to detect Down
syndrome in fetuses, but the accuracy of this method is unknown. ObjectiveTo determine the …
syndrome in fetuses, but the accuracy of this method is unknown. ObjectiveTo determine the …
The second-trimester fetus with Down syndrome: detection using sonographic features.
BR Benacerraf - Ultrasound in Obstetrics & Gynecology: the Official …, 1996 - europepmc.org
Down syndrome (trisomy 21) is the most common chromosomal abnormality among liveborn
infants in the United States, with an incidence of 1/700 to 1/1000 births. Its incidence rises …
infants in the United States, with an incidence of 1/700 to 1/1000 births. Its incidence rises …
Second trimester prenatal ultrasound for the detection of pregnancies at increased risk of Down syndrome
R Smith‐Bindman, P Chu… - … Diagnosis: Published in …, 2007 - Wiley Online Library
Objective To determine the association between second trimester ultrasound findings
(genetic sonogram) and the risk of Down syndrome. Methods Prospective population‐based …
(genetic sonogram) and the risk of Down syndrome. Methods Prospective population‐based …
The history of the second‐trimester sonographic markers for detecting fetal Down syndrome, and their current role in obstetric practice
BR Benacerraf - Prenatal diagnosis, 2010 - Wiley Online Library
This review summarizes the development, history and use of second‐trimester sonographic
markers for the detection of fetal Down syndrome over three decades. Starting with the …
markers for the detection of fetal Down syndrome over three decades. Starting with the …
Age‐adjusted ultrasound risk assessment for fetal Down's syndrome during the second trimester: description of the method and analysis of 142 cases
DA Nyberg, DA Luthy, RG Resta… - … in Obstetrics and …, 1998 - Wiley Online Library
Objective To describe and test a method of individual risk assessment for fetal Down's
syndrome based on maternal age and second‐trimester ultrasound findings. Design A case …
syndrome based on maternal age and second‐trimester ultrasound findings. Design A case …
The incorporation of maternal age into the sonographic scoring index for the detection at 14–20 weeks of fetuses with Down's syndrome
B Bromley, E Lieberman… - Ultrasound in Obstetrics …, 1997 - Wiley Online Library
Sonographic markers for Down's syndrome have been useful in the identification of affected
fetuses. In this study, we evaluated the accuracy of an expanded scoring index that included …
fetuses. In this study, we evaluated the accuracy of an expanded scoring index that included …
The role of the second trimester genetic sonogram in screening for fetal Down syndrome
BR Benacerraf - Seminars in perinatology, 2005 - Elsevier
The Genetic Sonogram is an ultrasound examination done on second trimester fetuses that
not only evaluates the fetus for structural malformations, but also searches for the …
not only evaluates the fetus for structural malformations, but also searches for the …
The genetic sonogram: a method of risk assessment for Down syndrome in the second trimester
B Bromley, E Lieberman, TD Shipp… - Journal of Ultrasound …, 2002 - Wiley Online Library
Objective. To determine the risk of Down syndrome in fetuses with sonographic markers
using the Bayes theorem and likelihood ratios. Methods. We prospectively evaluated the …
using the Bayes theorem and likelihood ratios. Methods. We prospectively evaluated the …
Role of prenatal ultrasonography in women with positive screen for Down syndrome on the basis of maternal serum markers
DA Nyberg, DA Luthy, EY Cheng, RC Sheley… - American Journal of …, 1995 - Elsevier
OBJECTIVE: Our purpose was to evaluate the usefulness of prenatal ultrasonography
among women with a positive screen for fetal Down syndrome on the basis of three …
among women with a positive screen for fetal Down syndrome on the basis of three …
Literature review and suggested protocol for managing ultrasound soft markers for Down syndrome: thickened nuchal fold, echogenic bowel, shortened femur …
M Bethune - Australasian radiology, 2007 - Wiley Online Library
Mid‐trimester soft markers have been linked with Down syndrome and other aneuploidies.
There are many other prenatal screening tests available with better detection rates for Down …
There are many other prenatal screening tests available with better detection rates for Down …
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