Current status and future of anti-angiogenic drugs in lung cancer

X Yan, Z Zhao, H Tang - Clinical and Experimental Medicine, 2023 - Springer
Lung cancer, as a malignant tumor with both high incidence and mortality in China, is one of
the major causes of death in our population and one of the major public health problems in …

Anti-angiogenic therapy in the treatment of non-small cell lung cancer

W Tian, C Cao, L Shu, F Wu - OncoTargets and therapy, 2020 - Taylor & Francis
Angiogenesis plays an essential role in the development of most solid tumors by delivering
nutrients and oxygen to the tumor. Therefore, anti-angiogenic therapy, particularly anti-VEGF …

[PDF][PDF] Antiangiogenic therapy: a novel approach to overcome tumor hypoxia

F Peng, M Chen - Chin J Cancer, 2010 - researchgate.net
Hypoxia is a common phenomenon in solid tumors, which can reduce the sensitivity of tumor
cells to radiotherapy and chemotherapy and, thus, is an important factor affecting cancer …

[HTML][HTML] Tumor angiogenesis: Current challenges and therapeutic opportunities

FH Al-Ostoot, S Salah, HA Khamees… - Cancer Treatment and …, 2021 - Elsevier
Angiogenesis plays an important role in the development of cancer since it allows for the
delivery of oxygen, nutrients, and growth factors as well as tumor dissemination to distant …

Molecular mechanisms of angiogenesis in non‐small cell lung cancer, and therapeutics targeting related molecules

S Yano, Y Nishioka, H Goto, S Sone - Cancer science, 2003 - Wiley Online Library
Angiogenesis, neovascularization from pre‐existing vasculature, is necessary to supply
oxygen and nutrition for tumor growth in both primary and distant organs. It consists of …

Targeting angiogenesis in cancer therapy

E Ichihara, K Kiura, M Tanimoto - Acta Medica Okayama, 2011 - ousar.lib.okayama-u.ac.jp
Angiogenesis is an essential process in tumor growth. The concept of angiogenesis, when
proposed by Folksman in 1971, had a great impact on cancer research and therapy, as the …

[HTML][HTML] Angiogenesis in lung cancer: understanding the roles of growth factors

TYS Ngaha, AV Zhilenkova, FE Essogmo, IK Uchendu… - Cancers, 2023 - mdpi.com
Simple Summary Growth factors promote angiogenesis, which is a critical process in the
development of tumors. One of the therapeutic techniques being investigated in the …

Antiangiogenic drugs: current knowledge and new approaches to cancer therapy

JL Mauriz, J González-Gallego - Journal of pharmaceutical sciences, 2008 - Elsevier
Angiogenesis—process of new blood-vessel growth from existing vasculature—is an
integral part of both normal developmental processes and numerous pathologies such as …

Antiangiogenic therapy for cancer: an update

B Al‐Husein, M Abdalla, M Trepte… - … : The Journal of …, 2012 - Wiley Online Library
The idea of antiangiogenic therapy was the brainchild of D r. J udah F olkman in the early
1970s. He proposed that by cutting off the blood supply, cancer cells would be deprived of …

[HTML][HTML] Potential therapeutic strategies for lung and breast cancers through understanding the anti-angiogenesis resistance mechanisms

WS Ramadan, DM Zaher, AM Altaie, IM Talaat… - International Journal of …, 2020 - mdpi.com
Breast and lung cancers are among the top cancer types in terms of incidence and mortality
burden worldwide. One of the challenges in the treatment of breast and lung cancers is their …